Summary
The intestinal Oxalobacter Formigenes were isolated in 30 cases of urolithiasis and in 45 controls. The biologic characters and morphology of the bacteria were also observed. The results showed that the colony counts in urolith group 9 (mean l03/g. faeces) were significantly less than that of controls (mean l08g. faeces) (P<0. 001). It is believed that the lesser amount of oxalobacter formigenes in urolith was the important factor of the calcium oxalate calculi formation.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Smith L H. The pathophysiology and medical treatment of urolothiasis. Semin Nephrol, 1990, 10: 31
Iarsson L. Hyperoxaluria. Miner Electrolyet Metab, 1987, 13: 242
Williams H E, Wandzila K. Oxalate synthesis, transport and the hyperoxaluric syndromes. J Urol, 1989, 141: 742
Alliaon M J, Cook H M, Milne DBet al. Oxalate degradation by gastrointestinal bacteria from humans. J Nutr, 1986, 116: 455
Dawson K A, Allison M J, Hartman P Aet al. Isolation and some characteristics of anaerobic oxalate-degrading bacteria from the rumen. Appl Environ Microbiol, 1980, 40: 833
Daniel S L, Hartman P A, Allison M Jet al. Mcrobial degradation of oxalate in the gastrointestional tracts of rats. Appl Envir Micro, 1987, 53(8): 1793
Argenzio R A, Liacos J A, Allison M Jet al. Intestinal oxalate-degrading bacteria ruduce oxalate absorption and toxicity in guinea pigs. J Nutri, 1988, 118: 787
Smith L H. Diet and hyperoxaluria in the syndrome of idiopathic calcium oxalate urolothiasis. Am J Kid Dis, 1991, 17(4): 370
Anantharam V, Allison M J, Maloney P Cet al. Oxalate: Formate Exchange. The basis for energy coupling in oxalobacter. J Bio Chem, 1989, 264(13): 7244
Ruan Z S, Anantharm V, Crawford I Tet al. Identification, purification, and reconstitution of Oxit, the Oxalate: Formate antiport protein of Oxalobacter Formigenes. J Bio Chem, 1992, 267(15): 10542
Baetz A L, Allison M J. Purification and characterization of Oxalyl-CoA decarboxylas from Oxalobacter Formigenes. J Bacteriology, 1989, 171(5):2605
Lung H Y, Cornrlius J G, Peck A Bet al. Cloning and expression the Oxalyl-CoA decarboxylase gene from the bacterium, Oxalobacyer Formigenes: Prospects for gene therapy to control Ca-oxalate kidney stone formation. Am J Kid Dis, 1991, 17(4): 381
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Jian-zhi, H., Xu, Z., Jia-gui, L. et al. The relationship of Oxalobacter Formigenes and calcium oxalate calculi. Journal of Tongji Medical University 15, 249–252 (1995). https://doi.org/10.1007/BF02887957
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02887957