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Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression

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Summary

To elucidate the mechanism of immunologic abnormalities induced by surgical trauma, we measured interleukin 2 (IL-2) production and IL-2 receptor expression in peripheral blood mononuclear cells from 16 patients with cholelithiasis. Compared with preoperative levels, IL-2 production and IL-2 receptor expression were significantly reduced on postoperative day 4, and the reduction was consistent with the suppression of lymphocyte proliferative response to phytohemagglutinin.

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Hua, L., Shu-tao, X., Shou-xi, Z. et al. Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression. Journal of Tongji Medical University 12, 160–163 (1992). https://doi.org/10.1007/BF02887817

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  • DOI: https://doi.org/10.1007/BF02887817

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