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Serum fructosamine in a random group of adult onset diabetics of Indian subpopulation

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Abstract

Serum fructosamine (SFRC) was estimated using single colour reading procedure in 50 normals and 160 adult onset random diabetics. Serum fructosamine levels were observed to be 1.86±0.321 m moles/L (Range 1.0 to 2.4) and 3.44±0.671 (Range 2.0 to 5.7) in normal and diabetic subjects respectively. Serum fructosamine levels as determined by the method adapted, were found to be unaffected by a transient rise in serum glucose levels during an oral glucose tolerance test. Significantly elevated SFRC concentration was also seen in diabetic groups in spite of different combinations of antidiabetic treatment. Attempts to correlate SFRC with duration and secondary complications of diabetes did show significant elevation in all the groups irrespective of duration and complications thus indicating poor glycemic control.

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Author notes

  1. Tangirala Malati Ph. D. (Associate Professor and Head)

    Present address: Department of Biochemistry, The Nizan’s Institute of Medical Sciences, Punjagutta, 500 482, Hyderabad, Andhra Pradesh, India

Authors and Affiliations

  1. Department of Biochemistry, The Nizan’s Institute of Medical Sciences, Punjagutta, 500 482, Hyderabad, Andhra Pradesh, India

    D. Murali Mohan Krishna

  2. ITL Biotech., Hyderabad, Andhra Pradesh, India

    B. Sadasivudu

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  1. Tangirala Malati Ph. D.
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  2. D. Murali Mohan Krishna
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  3. B. Sadasivudu
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Malati, T., Mohan Krishna, D.M. & Sadasivudu, B. Serum fructosamine in a random group of adult onset diabetics of Indian subpopulation. Indian J Clin Biochem 6, 51–57 (1991). https://doi.org/10.1007/BF02864965

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  • DOI: https://doi.org/10.1007/BF02864965

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