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Structure activity studies on the phenolic substrates in microsomal hydroxylation

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Abstract

Quantitative structure-activity relationships have been developed for three series of phenolic substrates viz. phenols, hydroxyindoles and tyramines in microsomal hydroxylation. The Fujita-Ban group contributions of various substituents have been calculated. Mono-, bi-and tri-substituted phenols have been investigated in the light of the linear free energy related model also.

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Singh, H., Gombar, V. & Jain, D.V.S. Structure activity studies on the phenolic substrates in microsomal hydroxylation. Proc. Indian Acad. Sci. (Chem. Sci.) 89, 77–86 (1980). https://doi.org/10.1007/BF02842326

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  • DOI: https://doi.org/10.1007/BF02842326

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