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Collagenolytic protease preparations from invertebrates: Biochemical aspects of medical and cosmetological applications

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Abstract

Collagenolytic proteases from invertebrates, the active matter of new structure-destroying enzyme preparations (Collagenase from hydrobionts, Polycollagenase-K, Fermenkol), ensure deep hydrolysis of polypeptide substrates (native or partially denatured collagen types, elastin, fibrin, hemoglobin, and casein) that cannot be attained by collagenases and serine proteases. Biochemical properties of collagenolytic proteases from invertebrates, techniques and doses that may be important for elaboration and employment of preparations based on this complex are described.

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Authors and Affiliations

  1. St. Petersburg-Technologiya, BioMed, St. Petersburg

    O. A. Klimova & V. Y. Chebotarev

Authors
  1. O. A. Klimova
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  2. V. Y. Chebotarev
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Correspondence to O. A. Klimova.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 7, pp. 70–75, July, 2000

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Klimova, O.A., Chebotarev, V.Y. Collagenolytic protease preparations from invertebrates: Biochemical aspects of medical and cosmetological applications. Bull Exp Biol Med 130, 671–675 (2000). https://doi.org/10.1007/BF02682102

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  • DOI: https://doi.org/10.1007/BF02682102

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