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Malignant transformation of human keratinocytes during adaptation to autotrophy

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References

  1. Agarwal, C.; Eckert, R. L. Immortalization of human keratinocytes by simian virus 40 large T-antigen alters keratin gene response to retinoids. Cancer Res. 50:5947–5953; 1990.

    PubMed  CAS  Google Scholar 

  2. Baden, H. P.; Kubilus, J.; Kvedar, J. C., et al. Isolation and characterization of a spontaneously arising long-lived line of human keratinocytes (NM1). In Vitro 23:205–213; 1987.

    CAS  Google Scholar 

  3. Boukamp, P.; Petrusevska, R. T.; Breitkreutz, D., et al. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106:761–771; 1988.

    Article  PubMed  CAS  Google Scholar 

  4. Danes, B. S.; Sutanto, E. Epithelial line from normal human colon mucosa. J. Natl. Cancer Inst. 69:1271–1276; 1982.

    PubMed  CAS  Google Scholar 

  5. DiPaolo, J. A.; Woodworth, C. D.; Popescu, N. C., et al. Induction of human cervical squamous cell carcinoma by sequential transfection with human papillomavirus 16 DNA and viral Harveyras. Oncogene 4:395–399; 1989.

    PubMed  CAS  Google Scholar 

  6. Dürst, M.; Dzarlieva-Petrusevska, R. T.; Boukamp, P., et al. Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene 1:251–256; 1987.

    PubMed  Google Scholar 

  7. Dürst, M.; Gallahan, D.; Jay, G., et al. Glucocorticoid-enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activatedras oncogene. Virology 173:767–771; 1989.

    Article  PubMed  Google Scholar 

  8. Fusenig, N. E.; Boukamp, P.; Breitkreutz, D., et al. Oncogenes and malignant transformation of human keratinocytes. In: Cerutti, P. A.; Nygaard, O. F.; Simic, M. G., eds. Anticarcinogenesis and radiation protection. New York-London: Plenum Press; 1987:227–231.

    Google Scholar 

  9. Hill, M.; Hillova, J.; Mariage-Samson, R. Autocrine factor-independent growth of mammalian fibroblasts in fully synthetic medium: no v-onc requirement in establishment. In Vitro 25:44–50; 1990.

    Google Scholar 

  10. Hillova, J.; Hill, M.; Nakamura, T., et al. Isolation of mammalian cellautotrophs able to grow indefinitely in protein-free chemically defined medium. Anticancer Res. 10:181–184; 1990.

    PubMed  CAS  Google Scholar 

  11. Hutchings, S. E.; Sato, G. H. Growth and maintenance of HeLa cells in serum-free medium supplemented with hormones. Proc. Natl. Acad. Sci. USA 75:901–904; 1978.

    Article  PubMed  CAS  Google Scholar 

  12. Kaur, P.; McDougall, J. K. Characterization of primary human keratinocytes transformed by human papillomavirus type 18. J. Virol. 62:1917–1924; 1988.

    PubMed  CAS  Google Scholar 

  13. Pecoraro, G.; Morgan, D.; Defendi, V. Differential effects of human papillomavirus type 6, 16, and 18 DNAs on immortalization and transformation of human cervical epithelial cells. Proc. Natl. Acad. Sci. USA 86:563–567; 1989.

    Article  PubMed  CAS  Google Scholar 

  14. Pirisi, L.; Creek, K. E.; Doniger, J., et al. Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA. Carcinogenesis 9:1573–1579; 1988.

    Article  PubMed  CAS  Google Scholar 

  15. Rhim, J. S.; Jay, G.; Arnstein, P., et al. Neoplastic transformation of human epidermal keratinocytes by AD12-SV40 and Kirsten sarcoma virus. Science 227:1250–1252; 1985.

    Article  PubMed  CAS  Google Scholar 

  16. Rhim, J. S.; Yoo, J. H.; Park, J. H., et al. Evidence for the multistep nature of in vitro human epithelial cell carcinogenesis. Cancer Res. 50:5653s-5657s; 1990.

    PubMed  CAS  Google Scholar 

  17. Ryle, C. M.; Breitkreutz, D.; Stark, H.-J., et al. Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and inras-transfected tumorigenic clones. Differentiation 40:42–54; 1989.

    Article  PubMed  CAS  Google Scholar 

  18. Thraves, P.; Salehi, Z.; Dritschilo, A., et al. Neoplastic transformation of immortalized human epidermal keratinocytes by ionizing radiation. Proc. Natl. Acad. Sci. USA 87:1174–1177; 1990.

    Article  PubMed  CAS  Google Scholar 

  19. Woodworth, C. D.; Bowden, P. E.; Doniger, J., et al. Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA. Cancer Res. 48:4620–4628; 1988.

    PubMed  CAS  Google Scholar 

  20. Woodworth, C. D.; Waggoner, S.; Barnes, W., et al. Human cervical and foreskin epithelial cells immortalized by human papillomavirus DNAs exhibit dysplastic differentiation in vivo. Cancer Res. 50:3709–3715; 1990.

    PubMed  CAS  Google Scholar 

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The work was supported by grants from the Association pour la Recherche sur le Cancer and from the Fondation pour la Recherche Médicale.

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Hill, M., Mariage-Samson, R. & Hillova, J. Malignant transformation of human keratinocytes during adaptation to autotrophy. In Vitro Cell Dev Biol - Animal 27, 270–272 (1991). https://doi.org/10.1007/BF02630901

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