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Mutagenic effect of vibration in combination with some chemical mutagens

  • Ecology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of vibration on the occurrence of micronuclei in bone marrow polychromatophile erythrocytes is examined in combination with the standard mutagens, benzene, orthoaminoazotoluol, quinoline, benzpyrene, and 2-acetaminofluorene. Mutagenic effect of benzpyrene was studied against the background of long-term (3 days or 2 months) vibration. Reduction in mutagenicity was observed with all studied agents. It was demonstrated that vibration modifies the effects of some mutagens and elicits effects opposite to those of the mutagens in the micronuclear test.

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Authors and Affiliations

  1. Medical, Center for Prevention and Protection of Health of Industrial Workers, Ekaterinburg, Russia

    N. V. Sigova, N. N. Vanchugova & V. N. Frash

Authors
  1. N. V. Sigova
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  2. N. N. Vanchugova
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  3. V. N. Frash
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 4, pp. 454–456, April, 1997

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Sigova, N.V., Vanchugova, N.N. & Frash, V.N. Mutagenic effect of vibration in combination with some chemical mutagens. Bull Exp Biol Med 125, 402–404 (1998). https://doi.org/10.1007/BF02499171

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  • DOI: https://doi.org/10.1007/BF02499171

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