Abstract
Proton magnetic resonance relaxation was experimentally studied in native blood serum in groups of healthy subjects and patients with malignant tumors. Although the longitudinal relaxation timeT 1 of the aqueous component in these groups was found to differ reliably, the longitudinal relaxation time of nonexchanging or slowly exchanging protons in these samples within the attained range of accuracy was virtually the same. Moreover, it was revealed that the amplitude of the “nonaqueous component” of blood serum correlates with the protein concentration in the samples.
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A. A. Vashman and I. S. Pronin, in:Nuclear Magnetic Relaxation and Its Use in Chemical Physics [in Russian], Moscow (1979), p. 44.
G. A. Galil-Ogly, G. I. Dmitriev, N. F. Karyakina,et al., Vest. Akad. Med., Nauk SSSR, No 12, 43–46 (1987).
A. K. Zhuravlev and M. G. Gangardt,Molek. Biol.,21, 434–441 (1987).
L. I. Murza, A. I. Sergeev, A. F. Vanin,et al., Dokl. Akad. Nauk SSSR,237, 1216–1218 (1977).
L. I. Murza, A. I. Sergeev, V. I. Naidich,et al.,,254, 614–617 (1980).
O. P. Revokatov, M. G. Gangardt, I. I. Murashko, and A. K. Zhuravlev,Biofizika,27, Issue 2, 336–338 (1982).
R. Damadian,Science.,171, 1151 (1971).
B. Halle, N. Anderssen, S. Forsen, and B. Lindman,J. Amer. Chem. Soc.,103, No 3, 500–508 (1981).
S. H. Koenig, R. Bryant, K. Hallenga, and S. Jacob,Biochemistry,17, No 20, 4348–4358 (1978).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 10, pp. 445–448, October, 1995
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Gangardt, M.G., Karyakina, N.F., Pavlov, A.S. et al. Proton NMR relaxation of the nonaqueous component of human blood serum. Bull Exp Biol Med 120, 1073–1076 (1995). https://doi.org/10.1007/BF02444990
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DOI: https://doi.org/10.1007/BF02444990