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Relationship between hemoglobin affinity for oxygen and lipid peroxidation in fever

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Hemoglobin affinity for oxygen (P50 parameter) and the content of malonic dialdehyde (MDA), Schiff's bases, and diene conjugates in the plasma and red cell mass were examined in mixed venous blood of rabbits with pyrogenal fever. Correlation regression analysis of the tested parameters showed that reduction of the actual affinity of hemoglobin for oxygen is conducive to activation of free-radical processes.

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Authors and Affiliations

  1. Department of Biophysics, Grodno Medical Institute, Grodno, USSR

    M. V. Borisyuk, V. V. Zinchuk, V. N. Korneichuk & I. N. Galushko

Authors
  1. M. V. Borisyuk
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  2. V. V. Zinchuk
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  3. V. N. Korneichuk
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  4. I. N. Galushko
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 7, pp. 27–30, July, 1994

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Borisyuk, M.V., Zinchuk, V.V., Korneichuk, V.N. et al. Relationship between hemoglobin affinity for oxygen and lipid peroxidation in fever. Bull Exp Biol Med 118, 707–710 (1994). https://doi.org/10.1007/BF02444363

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  • DOI: https://doi.org/10.1007/BF02444363

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