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Inhibition of mitogen-stimulated proliferation of human lymphocytesin vitro by synthetic peptide fragments of α-2 interferon

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Human α-2 interferon and peptides representing parts of the amino-acid sequence 124–138 of the IF molecule inhibit the proliferative response of peripheral blood lymphocytes from healthy donorsin vitro induced by ConA. It is shown that neither interferon α-2 nor biologically active peptides change the level of interleukin-2 ConA-induced production by human blood mononuclears.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 1, pp. 72–74, January, 1994

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Danilkovich, A.V., Freze, K.V., Targoni, O.S. et al. Inhibition of mitogen-stimulated proliferation of human lymphocytesin vitro by synthetic peptide fragments of α-2 interferon. Bull Exp Biol Med 117, 75–78 (1994). https://doi.org/10.1007/BF02444086

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  • DOI: https://doi.org/10.1007/BF02444086

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