Abstract
The interactions between tumor cells and autoantibodies to tumor-associated human ovarian cancer antigen isolated from the plasma of a non-cancer patient are demonstrated using an original model of pseudomucinous murine ovarian carcinoma CaO-1. The use of natural auto-antibodies for active immunotherapy of tumors may be more effective and safe than murine monoclonal antibodies to CA 125, because there will be no reaction to a foreign protein.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 2, pp. 227–229, February, 1999
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Amandzholov, B.S., Lebedin, Y.S., Chukanov, S.V. et al. Interactions between natural autoantibodies to tumor-associated human ovarian cancer antigen and murine ovarian cancer cells CaO-1. Bull Exp Biol Med 127, 206–208 (1999). https://doi.org/10.1007/BF02433117
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DOI: https://doi.org/10.1007/BF02433117