Abstract
Two meiotic genes from natural populations are described. A female meiotic mutation,mei(1)g13, mapped to 17.4 on the X chromosome, causes nondisjunction of all homologs except for the fourth chromosomes. In addition, it reduces recombination by 10% in the homozygotes and causes 18% increased recombination in the heterozygotes. A male meiotic mutation,mei-1223 m144, is located on the third chromosome. Although this mutation causes nondisjunction of all chromosomes, each chromosome pair exhibits a different nondisjunction frequency. Large variations in the sizes of the premature sperm heads observed in the homozygotes may reflect irregular meiotic pairing and the subsequent abnormal segregation, resulting in aneuploid chromosome complements.
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Yamamoto, A.H., Muramatsu, K., Otsuka, T. et al. Meiotic mutations from natural populations ofDrosophila melanogaster . Genetica 88, 165–173 (1993). https://doi.org/10.1007/BF02424473
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DOI: https://doi.org/10.1007/BF02424473