Skip to main content
Log in

The correlation between muscle magnetic resonance images and histopathological findings in a patient with myotonic dystrophy

  • Published:
Medical Electron Microscopy Aims and scope Submit manuscript

Abstract

We examined the correlation between magnetic resonance images (MRI) and histopathological findings in a patient with myotonic dystrophy. Tl-weighted images showed more severe abnormalities in the distal muscles than in the proximal muscles in the lower extremity. Histopathological examination showed the progression of muscle disorganization, degeneration, necrosis and atrophy in areas in which the distribution of high intensity signals was increased on Tl-weighted images. Our findings suggest that histopathological changes in the muscles of patients with myotonic dystrophy can be evaluated using Tl-weighted images.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Carpenter, S. andKarpati, G.: Methods of tissue removal and preparation.In: Pathology of Skeletal Muscle (Carpenter, S. andKarpati, G. ed.), p. 36–61, Churchill Livingstone, London, 1984.

    Google Scholar 

  2. Rodiek, S.O.: Kernspintomographie der Skelettmuskulatur bei neuromuskularen Erkrankungen.Fortschr. Röntgenstr. 143, 418–425 (1985).

    CAS  Google Scholar 

  3. Rodiek, S.O., Kuther G., Kuretschke, H.P., Hoepfel, D. undSchuff, N.: MR-Tomographie und-Spektroskopie der Skelettmuskulatur bei hohen Magnetfeldstarken.Fortschr. Röntgenstr. 144, 89–94 (1986).

    CAS  Google Scholar 

  4. Damian, M.S., Bachmann, G., Herrmann, D. andDorndorf, W.: Magnetic resonance imaging of muscle and brain in myotonic dystrophy.J. Neurol. 240, 8–12, (1993).

    Article  CAS  PubMed  Google Scholar 

  5. Åström, K.E. andAdams, R.D.: Myotonic disorders.In: Skeletal Muscle Pathology (Mastaglia, F.L. andWalton, J. ed.), p. 266–286, Churchill Livingstone, London, 1982.

    Google Scholar 

  6. Carpenter, S. andKarpati, G.: Myotonic dystrophy-adult.In: Pathology of Skeletal Muscle (Carpenter, S. andKarpati, G. ed.), p. 616–627, Churchill Livingstone, London, 1984.

    Google Scholar 

  7. Daniels, D.L. andHaughton, U.M.: Guidelines to interpreting cranial magnetic resonance images.In: Cranial and Spinal Magnetic Resonance Imaging. An Atlas and Guide (Daniels, D.L., Haughton, V.M. andNaidich, T.P. ed.), p. 5–20, Raven Press, New York, 1987.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hayashi, R., Hayashi, K., Maruyama, K. et al. The correlation between muscle magnetic resonance images and histopathological findings in a patient with myotonic dystrophy. Med Electron Microsc 27, 145–148 (1994). https://doi.org/10.1007/BF02348179

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02348179

Key words

Navigation