Abstract
This study explored whether benzodiazepines selectively affect aspects of attention and/or visual information processing, as they do memory. A cued visual-search paradigm was employed, using normal volunteers and a single dose of triazolam. This paradigm provided for a detailed examination of two aspects of visual attention and information processing: 1) controlled versus automatic attention allocation (via central and peripheral cues), and 2) the extent to which processing an item in a non-cued location affects performance (via cue-validity). Triazolam, compared to placebo, significantly increased response time, and Drug Condition interacted with Cue-Validity but not Cue-Type. Based on these data, we argue that triazolam doesnot affect attention allocation butdoes affect attentional disengagement and/or attention switching mechanisms.
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References
Birch B, Curran HV (1990) The differential effects of flumazenil on the psychomotor and amnesic actions of midazolam. Psychopharmacology 4:29–34
Cave KR, Wolfe JM (1990) Modeling the role of parallel processing in visual search. Cognitive Psychology 22:225–271
Curran HV (1986) Tranquillizing memories: A review of the effects of benzodiazepines on human memory. Biol Psychol, 23:179–213
Curran HV, Birch B (1991) Differentiating the sedative, psychomotor and amnesic effects of benzodiazepines: a study with midazolam and the benzodiazepine antagonist, flumazenil. Psychopharmacology 103:519–523
Danion JM, Zimmermann MA, Willard-Schroeder D, Grange D, Singer L (1989) Diazepam induces a dissociation between explicit and implicit memory. Psychopharmacology 99:238–243
Eriksen CW, Hoffman JE (1974) Selective attention: Noise suppression or signal enhancement? Bulletin of Psychonomic Society 4(6) 587–589
Hommer D, Weingartner HJ, Brier A (1993) Dissociation of benzodiazepine induced amnesia from sedation Psychopharmacology 112:455–460
Johnson DN, Yantis S (1995) Allocating visual attention: tests of a perceptual sampling model. J Exp Psychol [Hum Percept Perform] (in press)
Jonides J (1980) Towards a model of the mind's eye's movement. Can J Psychol 34:103–112
Jonides J (1981) Voluntary vs. automatic control over the mind's eye's movement. In: Long JB, Baddeley AD (eds) Attention and performance IX Erlbaum Hillsdale, N.J. pp 187–203
Jonides J (1983) Further toward a model of the mind's eye's movement. Bull Psychon Soc 21:247–250
Lister RG, Weingartner H, Eckardt MJ, Linnoila M (1988) Clinical relevance of effects of benzodiazepines on learning and memory. In: Hindmarch I, Oh H (eds) Benzodiazepine receptor ligands, memory and information processing. Springer, Berlin pp. 117–127
Müller HJ, Rabbitt PMA (1989) Reflexive and voluntary orienting of visual attention: Time course of activation and resistance to interruption. J Exp Psychol Hum Percept Perform 15:315–330
Posner MI, Snyder CR, Davidson BJ (1980) Attention and the detection of signals. J Exp Psychol [General] 109(2):160–174
Spitzer RL, Williams JBW, Gibbon M, First MD (1990) Structured clinical interview for DSM-III-R. American Psychiatric Association Press, Washington, DC
Treisman AM, Gelade, G (1980) A feature-integration theory of attention. Cognitive Psychology 12(1):97–136
Weingartner HJ, Joyce EM, Adams CM, Eckardt MJ, George T, Lister RG (1995) Effects of the benzodiazepine triazolam on different forms of memory and sedation. J Psychopharmacol (in press)
Wolfe JM, Cave KR, Franzel SL (1989) Guided search: an alternative to the feature integration model for visual search. J Exp Psychol [Hum Percept Perform] 15:419–433
Yantis S, Johnson DN (1990) Mechanisms of attentional priority. J Exp Psychol [Hum Percept Perform] 16:812–825
Yantis S, Jonides J (1990) Abrupt visual onsets and selective attention: voluntary versus automatic attention allocation. J Exp Psychol [Hum Percept Perform] 16:121–134
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Johnson, D.N., Weingartner, H.J., Andreason, P. et al. An effect of triazolam on visual attention and information processing. Psychopharmacology 121, 145–149 (1995). https://doi.org/10.1007/BF02245623
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DOI: https://doi.org/10.1007/BF02245623