Abstract
Analysis of discrete distributions of basic EPSP amplitudes at sensorimotor, proprio- and reticulo-motoneuronal synapses in the frog by means of the convolution of two binomial distributions revealed that the number of transmitter release sites operating was greater than that calculated by means of binomial distribution. Probability levels of transmitter release sites responding in unison to nerve impulses are dissimilar (at not more than 0.1–0.3) and remained constant. Interference with the release mechanism induced blockade of release sites. Impairment of the process triggering transmitter release produced a sharp decline in the probability of release sites operating in unison.
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Additional information
A. A. Zhdanov State University, Leningrad; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of the USSR, Leningrad. Translated from neirofiziologiya, Vol. 20, No. 4, pp. 487–494, July–August, 1988.
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Bart, A.G., Dityatev, A.É. & Kozhanov, V.M. Analysis of transmission at interneuronal synapses using a convolution of binomial distributions. Neurophysiology 20, 357–363 (1988). https://doi.org/10.1007/BF02198444
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DOI: https://doi.org/10.1007/BF02198444