Abstract
The results of local beta ray radiation of 295 eyes containing a uveal melanoma (including 74 melanomas of the anterior choroid and ciliary body) are presented with special respect to the complications of treatment. The most frequent complications were radiation retinopathy and optic neuropathy. Complications known to occur from other radiation methods, such as dry eye syndrome, loss of cilia, and scleral necrosis, did not occur in our series. The incidence of radiation cataract, as compared to the treatment with60Co plaques, was lower in our series. An average of 700 Gy delivered to the scleral base of the tumor was needed for uveal melanomas which could be destroyed. This radiation dose resulted in a 10% incidence of radiation retinopathy.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Brown GC, Shields JA, Sanborn G, Augsburger JJ, Savino PJ, Schatz NJ (1982a) Radiation optic neuropathy. Ophthalmology 89: 1489–1493
Brown GC, Shields JA, Sanborn G, Augsburger JJ, Savino PJ, Schatz NJ (1982b) Radiation retinopathy. Ophthalmology 89: 1494–1501
Fine SL (1985) How should we manage a patient with a uveal melanoma? Arch Ophthalmol 103: 910–911
Foerster MH, Wessing A, Meyer-Schwickerath G (1983) The treatment of ciliary body melanoma by beta radiation. Trans Ophthalmol Soc UK 103: 64–67
Gragoudas ES, Seddon J, Goitein M, Verhey L, Munzenrider J, Urie M, Suit HD, Blitzer P, Koehler A (1985) Current results of proton beam irradiation of uveal melanomas. Ophthalmology 92: 284–291
Lommatzsch P (1974) Treatment of choroidal melanomas with Ru 106/Rh 106 beta ray applicators. Surv Ophthalmol 19: 85–100
Lommatzsch PK (1979) Radiotherapie der intraokularen Tumoren, insbesondere bei Aderhautmelanom. Klin Monatsbl Augenheilkd 174: 948–958
Lommatzsch PK (1983) β-Irradiation of choroidal melanoma with106Ru/106Rh applicators: 16 years' experience. Arch Ophthalmol 101: 713–717
MacFaul PA (1977) Local radio-therapy in the treatment of malignant melanoma of the choroid. Trans Ophthalmol Soc UK 97: 421–427
MacFaul PA, Bedford MA (1970) Ocular complications after therapeutic irradiation. Br J Ophthalmol 54: 237–247
Noble KG, Kupersmith MJ (1984) Retinal vascular remodelling in radiation retinopathy. Br J Ophthalmol 68: 475–478
Packer S, Rotman M (1980) Radiotherapy of choroidal melanoma with iodine-125. Ophthalmology 87: 582–590
Rotman M, Long RS, Packer S, Moroson H, Galin MA, Chan B (1977) Radiation therapy of choroidal melanoma. Trans Ophthalmol Soc UK 97: 431–435
Rotman M, Packer S, Long R, Chiu-Tsao ST, Sedhom LZ (1983) Opththalmic plaque irradiation of choroidal melanoma. In: Lommatzsch PK, Blodi FC (eds) Intraocular tumors (Fortschritte der Onkologie, vol 9). Akademie, Berlin, pp 341–346
Schmidt M (1977) Zur Beta-Dosimetrie medizinischer Applikatoren. Isotopenpraxis 12: 413–418
Shields JA (1977) Modern methods in the diagnosis of uveal melanomas. Trans Ophthalmol Soc UK 97: 407–411
Shields JA, Augsburger LW, Brady LW, Day JL (1982) Cobalt plaque therapy of posterior uveal melanomas. Ophthalmology 89: 1201–1207
Stallard HB (1960) Malignant melanoma of the choroid treated with radioactive applicators. Trans Ophthalmol Soc UK 79: 373–392
Stallard HB (1966) Radiotherapy for malignant melanoma of the choroid. Br J Ophthalmol 50: 147–155
Zografos L, Gailloud CL (1979) Traitement conservateur des melanomes choroidiens par radiothèrapie de contact. Klin Monatsbl Augenheilkd 174: 927–933
Zografos L, Gailloud CL (1983) Conservative treatment of choroidal melanoma by cobalt 60 applicators. In: Lommatzsch PK, Blodi FC (eds) Intraocular tumors (Fortschritte der Onkologie, vol 9). Akademie, Berlin, pp 286–289
Zygulska-Mach H, Maciejewski Z, Link E (1983) Conservative treatment of choroidal melanomas combined use of cobalt plaques and photocoagulation. In: Lommatzsch PK, Blodi FC (eds) Intraocular tumors (Fortschritte der Onkologie, vol 9). Akademie, Berlin, pp 417–423
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Foerster, M.H., Bornfeld, N., Schulz, U. et al. Complications of local beta radiation of uveal melanomas. Graefe's Arch Clin Exp Ophthalmol 224, 336–340 (1986). https://doi.org/10.1007/BF02150026
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02150026