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Severe hypertensive reaction after naloxone injection during labor

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Summary

A case of severe hypertension during labor after Naloxone injection is described in a patient with previous mild hypertension. The interaction of andogenous opioids and opiate antagonists, and their role in the control of blood pressure is discussed. Opiate antagonists should be given with caution to obstetric patients with mild to moderate hypertension.

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Schoenfeld, A., Friedman, S., Stein, L.B. et al. Severe hypertensive reaction after naloxone injection during labor. Arch. Gynecol. 240, 45–47 (1987). https://doi.org/10.1007/BF02134063

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