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The effect of cobra venom factor (CVF) activation of the complement cascade on leukocyte circadian variation in the rat

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Summary

Administration of cobra venom factor (CVF) at different time periods over a 24-h-period produced a leukocytic response which varied according to the time of day the factor was given. The resulting leukocytic circadian rhythm was achieved by a marked variation and increase in the neutrophil population.

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References

  1. H. J. Muller-Eberhard, in: Progress in Immunology. Ed. B. Amos. Academic Press, New York 1971.

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Authors and Affiliations

  1. Department of Medicine, Bowman Gray School of Medicine, Wake Forest University, 27103, Winston-Salem, North Carolina, USA

    Phillip C. Hoopes & Charles E. McCall

Authors
  1. Phillip C. Hoopes
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  2. Charles E. McCall
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Additional information

This study was supported by U. S. P. H. S. Grant No. HL 16769 and Grant No. AI 09169.

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Hoopes, P.C., McCall, C.E. The effect of cobra venom factor (CVF) activation of the complement cascade on leukocyte circadian variation in the rat. Experientia 33, 224–226 (1977). https://doi.org/10.1007/BF02124080

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  • DOI: https://doi.org/10.1007/BF02124080

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