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Morphological changes in thioglycerol-treatedEscherichia coli

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Abstract

Extended exposure ofEscherichia coli 15 THU to 1-thioglycerol resulted in morphological changes. Cells growing with 10 mM 1-thioglycerol were shorter in the stationary phase than untreated organisms. Sixty mM 1-thioglycerol caused the appearance of double cells connected with constricted septal regions. Electron microscopic examination of the elongated cells failed to show septal structures. The specific cause of the appearance of constricted bridges between cells may be the inhibition of ftsA protein by 60 mM 1-thioglycerol.

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Javor, G.T. Morphological changes in thioglycerol-treatedEscherichia coli . Current Microbiology 20, 57–62 (1990). https://doi.org/10.1007/BF02094026

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