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Intracranial saccular aneurysms results of treatment in 851 patients

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Summary

The series studied comprises all 851 patients with symptom-producing intracranial saccular aneurysms admitted to the departments of neurosurgery in Denmark in the five-year period of 1970–1974. The series was divided into seven clinical stages according to Hunt's classification. More than half of the patients were grouped in stages IV and V (Hunt grade 2–3). Of the patients, 76% were found primarily suitable for operation. The mortality within the individual stages was to a great extent independent of the time of operation.

A total of 94% of the aneurysms were localized within the region of the carotid artery, with a roughly equal distribution among the internal carotid, anterior communicating, and middle cerebral arteries. Multiple aneurysms were found in 19% of the patients subjected to panangiography.

There was a distinct correlation between the severity of the spasms and the clinical condition. The course of operation was complicated in 49% of the patients, the complications being equally distributed within the various clinical stages. The mortality for the patients who underwent operation (total 567) was 32%, and 80% of the deaths were due to direct or indirect consequences of aneurysmal bleeding.

At the follow-up performed two to seven years after operation, 52% of the survivors were fully capacitated, 20% were partly capacitated, and 28% were incapacitated. Based on a retrospective analysis, we have started a comprehensive prospective study with registration of available parameters in patients with saccular aneurysms admitted to all departments of neurosurgery in Denmark.

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References

  1. Dott, N. M., Intracranial aneurysms, cerebral angiography, surgical treatment. Edinb. Med. J.40 (1933), 219–240.

    Google Scholar 

  2. Graf, C.-J., Nibbelink, D. W., Cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Report on a randomized treatment study III. Intracranial surgery. Stroke5 (1974), 559–601.

    Google Scholar 

  3. Hunt, W. E., Grading risk in intracranial aneurysms. In: Recent progress in neurological surgery (Sano, K., Ishii, S., eds.), International Congress Series, No. 320. Amsterdam: Excerpta Medica. 1974.

    Google Scholar 

  4. Kaste, M., Troupp, H., Subarachnoid hemorrhage: Long-term follow-up results of late versus conservative treatment. Brit. Med. J.1 (1978), 1310–1311.

    PubMed  Google Scholar 

  5. Locksley, H. B., Natural history of subarachnoid hemorrhage, intracranial aneurysms and arteriovenous malformations. Based on 6,368 cases in the cooperative study. J. Neurosurg.25 (1966), 321–368.

    PubMed  Google Scholar 

  6. McKissock, W., Paine, K. W. E., Walsh, L. S., An analysis of the results of treatment of ruptured intracranial aneurysms. Report of 772 consecutive cases. J. Neurosurg.17 (1960), 762–776.

    Google Scholar 

  7. Moniz, E., L'encéphalographie artérielle, son importance dans la localisation des tumeurs cérébrales. Rev. Neurol.2 (1927), 72–90.

    Google Scholar 

  8. Nibbelink, D. W., Torner, J. C., Henderson, W. G., Intracranial aneurysms and subarachnoid hemorrhage. A cooperative study. Antifibrinolytic therapy in recent onset subarachnoid hemorrhage. Stroke6 (1975), 622–629.

    PubMed  Google Scholar 

  9. Nibbelink, D. W., Torner, J. C., Henderson, W. G., Intracranial aneurysms and subarachnoid hemorrhage. Report on a randomized treatment study IV A. Regulated bed test. Stroke8 (1977), 202–218.

    PubMed  Google Scholar 

  10. Pakarinen, S., Incidence, aetiology and prognosis of primary subarachnoid hemorrhage. A study based on 589 cases diagnosed in a defined urban population during a defined period. Acta Neurol. Scand. pp. 128,43, Supplementum 29, 1967.

    Google Scholar 

  11. Skultety, F. M., Nishioka, H., The results of intracranial surgery in the treatment of aneurysms. J. Neurosurg.25 (1966), 683–704.

    Google Scholar 

  12. Sundt, T. M., Whisnant, J. P., Subarachnoid hemorrhage from intracranial aneurysms. Surgical management and natural history of disease. New Engl. J. Med.299 (1978), 116–122.

    PubMed  Google Scholar 

  13. Troupp, H., Björkesten, G. af, Results of a controlled trial of late surgical versus conservative treatment of intracranial arterial aneurysms. J. Neurosurg.35 (1971), 20–24.

    PubMed  Google Scholar 

  14. Werf, A. J. M. van der, Clinical aspects of subarachnoid hemorrhage and significance of vasospasm. Psychiat. Neurol. Neurochir.75 (1972), 411–415.

    PubMed  Google Scholar 

  15. Winn, H. R., Richardson, A. E., Jane, J. A., Long-term prognosis in untreated cerebral aneurysms: The incidence of late hemorrhage in cerebral aneurysm: A 10-year evaluation of 364 patients. Ann. Neurol.1 (1977), 358–370.

    PubMed  Google Scholar 

  16. Yoshimoto, T., Uchida, K., Kaneko, U., Kayama, T., Suzuki, J., An analysis of follow-up results of 1,000 intracranial saccular aneurysms with definitive surgical treatment. J. Neurosurg.50 (1979), 152–157.

    PubMed  Google Scholar 

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Rasmussen, P., Busch, H., Haase, J. et al. Intracranial saccular aneurysms results of treatment in 851 patients. Acta neurochir 53, 1–17 (1980). https://doi.org/10.1007/BF02074516

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