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Histiocytic cytophagic panniculitis: Report of a case in a 12-year-old girl

  • Hematology/Oncology
  • Published:
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Abstract

We report a 12-year-old girl with nodular skin lesions, fever, pancytopenia, coagulation defects and a fatal outcome within 4 months. Histopathology revealed proliferation of histiocytes with haemophagocytosis in skin, perivisceral fat and haemopoietic organs. The symptoms were most consistent with cytophagic histiocytic panniculitis.

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References

  1. Alegre VA, Winkelmann RK (1989) Histiocytic cytophagic panniculitis. J Am Acad Dermatol 20: 177–185

    PubMed  Google Scholar 

  2. Barron DR, Davis BR, Pomeranz JR, Hines JD, Park CH (1985) Cytophagic histiocytic panniculitis. A Variant of malignant histiocytosis. Cancer 55:2538–2542

    PubMed  Google Scholar 

  3. Crotty CP, Winkelmann RK (1981) Cytophagic histiocytic panniculitis with fever, cytopenia, liver failure, and terminal hemorragic diathesis. J Am Acad Dermatol 4:181–194

    PubMed  Google Scholar 

  4. Margolick JB, Ambrus JL, Volkman DJ, Fauci AS (1986) Human T4 lymphocytes produce a phagocytosis-inducting factor (PIF) distinct from interferon-gamma. J Immunol 136:546–554

    PubMed  Google Scholar 

  5. Oyama Y, Amano T, Hirakawa, S, Hironaka K, Suzuki S, Ota Z (1989) Haemophagocytic syndrome treated with cyclosporin A: a T cell disorder? Br J Haemato 73:276–278

    Google Scholar 

  6. Peters MS, Winkelmann RK (1985) Cytophagic panniculitis and B cell lymphoma. J Am Acad Dermatol 13:882–885

    PubMed  Google Scholar 

  7. Willis SM, Opal SM, Fitzpatrick JE (1985) Cytophagic Histiocytic panniculitis. Systemic histiocytosis presenting as chronic, nonhealing, ulcerative skin lesions. Arch Dermatol 121: 910–913

    Article  PubMed  Google Scholar 

  8. Winkelmann RK, Bowie EJ (1980) Hemorragic diathesis associated with benign histiocytic, cytophagic and systemic histiocytosis. Arch Intern Med 140:1460–1463

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Paediatrics, La Paz Hospital, Paseo de la Castellana 261, E-28046, Madrid, Spain

    J. Garcia-Consuegra & M. I. Barrio

  2. Department of Dermatology, La Paz Hospital, Paseo de la Castellana 261, E-28046, Madrid, Spain

    E. Fonseca

  3. Department of Pathology, La Paz Hospital, Paseo de la Castellana 261, E-28046, Madrid, Spain

    J. I. Rodriguez & F. Contreras

Authors
  1. J. Garcia-Consuegra
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  2. M. I. Barrio
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  3. E. Fonseca
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  4. J. I. Rodriguez
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  5. F. Contreras
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Garcia-Consuegra, J., Barrio, M.I., Fonseca, E. et al. Histiocytic cytophagic panniculitis: Report of a case in a 12-year-old girl. Eur J Pediatr 150, 468–469 (1991). https://doi.org/10.1007/BF01958423

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  • DOI: https://doi.org/10.1007/BF01958423

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