Summary
A new histidine decarboxylase inhibitor, thiazol-4-ylmethoxyamine (TMA), injected into mice in a dose of 100 mg/kg i.p. 48 h before the implantation of a morphine-containing pellet, inhibited the development of morphine tolerance and physical dependence.
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I thank the World Health Foundation (Hong Kong) for a grant in aid of this research.
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Hui, KS. The effect of thiazol-4-ylmethoxyamine, a histidine decarboxylase inhibitor, on the development of morphine tolerance and physical dependance in mice. Experientia 32, 1313–1315 (1976). https://doi.org/10.1007/BF01953112
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DOI: https://doi.org/10.1007/BF01953112