Summary
Bunaphtide induces a blockade in the3H-norepinephrine uptake and retention in the isolated guinea-pig left atrium. However, this blockade does not seems to be related with the cardiodepressant effect of the drug.
Similar content being viewed by others
References
L. Beani and A. Ferroni, Acts of the Eur. Congress of Cardiol., Madrid, 1972, p. 23.
A. Ferroni and G. Monticelli, Pharmac. Res. Commun.5, 151 (1973).
J. Tamargo, J. Manzanero, J. Beneit and P. Garcia de Jalón, IIa Reunion Asoc. Esp. de Farmac., Cádiz, 1976, p. 53.
P. Garcia de Jalón, J. P. Moratinos and J. Serrano, Br. J. Pharmac.46, 167 (1972).
H. A. Krebs and K. Z. Henseleit, J. Phys. Chem., Ithaca210, 33 (1932).
A. H. Anton and D. F. Sayre, J. Pharmac. exp. Ther.138, 360 (1962).
A. R. Wakade and R. F. Furchgott, J. Pharmac. exp. Ther.163, 123 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Barrigón, S., Tamargo, J. & Garcia de Jalón, P.D. Interaction of cocaine and bunaphtide on the3H-norepinephrine uptake mechanism on isolated left atrium of guinea-pig. Experientia 34, 770 (1978). https://doi.org/10.1007/BF01947316
Issue Date:
DOI: https://doi.org/10.1007/BF01947316