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The free radical oxidation of the tetrahydrocannabinols

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Summary

The free radical oxidation of Δ1 and Δ6-tetrahydrocannabinol has been examined by spin trapping techniques and intermediates that would lead to cannabinol have been trapped. The 1st step in the oxidation of Δ1-THC involves the removal of 3-H, while for Δ6-THC, either 2-H or 5-H. Intermediates were isolated which could be pyrolysed to the diene and cannabinol.

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Authors and Affiliations

  1. Chemistry Division, Department of Scientific and Industrial Research, Private Bag, Petone, New Zealand

    I. J. Miller, N. K. McCallum, C. M. Kirk & B. M. Peake

  2. Chemistry Department, University of Otago, Dunedin, New Zealand

    I. J. Miller, N. K. McCallum, C. M. Kirk & B. M. Peake

Authors
  1. I. J. Miller
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  2. N. K. McCallum
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  3. C. M. Kirk
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  4. B. M. Peake
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Miller, I.J., McCallum, N.K., Kirk, C.M. et al. The free radical oxidation of the tetrahydrocannabinols. Experientia 38, 230–231 (1982). https://doi.org/10.1007/BF01945081

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