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Elevated glucose levels influence in vitro hatching, attachment, trophoblast outgrowth and differentiation of the mouse blastocyst

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Summary

A glucose concentration of 3.5 mg/ml is optimal for in vitro embryo attachment and trophoblastic cell outgrowth. Raising the concentration above 3.5 mg/ml does not improve embryo culture and can at certain concentrations be detrimental to embryo development.

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Author notes

  1. R. J. Wordinger

    Present address: Pathology Division, National Center for Toxicological Research, 72079, Jefferson, Arkansas, USA

Authors and Affiliations

  1. Department of Biology, St. Bonaventure University, 14778, St. Bonaventure, New York, USA

    R. J. Wordinger & J. A. Kell

Authors
  1. R. J. Wordinger
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  2. J. A. Kell
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Wordinger, R.J., Kell, J.A. Elevated glucose levels influence in vitro hatching, attachment, trophoblast outgrowth and differentiation of the mouse blastocyst. Experientia 34, 881–882 (1978). https://doi.org/10.1007/BF01939680

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  • DOI: https://doi.org/10.1007/BF01939680

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