Skip to main content
SpringerLink
Log in

Reduced foetal calcium without skeletal malformations in rats following high maternal doses of a strontium salt

  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

nachweis, dass hohe Strontiumkonzentrationen die Kalzifikation der, Knochen neugeborener Mäuse, und diejenige in Knochengewebskulturen hemmen. Im Gegensatz dazu und zu anderen knochenaffinen metallen wirkt Strontiumnitrat in Dosen von25, 50, 100 and 200 mg/kg, verabreicht während des 9. bis 19. Trächtigkeitstages, bei Ratten nicht teratogen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. V. H. Ferm andS. J. Carpenter, Expl molec. Path.7, 208 (1967).

    Article  Google Scholar 

  2. V. H. Ferm, Experientia25, 26 (1969).

    Article  PubMed  Google Scholar 

  3. V. H. Ferm andS. J. Carpenter, Lab. Invest.18, 429 (1968).

    PubMed  Google Scholar 

  4. R. E. Holmberg andV. H. Ferm, Arch. envir Hlth.18, 873 (1969).

    Google Scholar 

  5. H. Fries, Lancet1, 1233 (1970).

    Article  Google Scholar 

  6. K. T. Szabo, Lancet2, 849 (1969).

    Article  Google Scholar 

  7. K. T. Szabo, Nature, Lond.225, 73 (1970).

    Google Scholar 

  8. O. Rygh, Bull. Soc. Chim. biol.31, 1052 (1949).

    Google Scholar 

  9. E. Browning, inThe Toxicity of Industrial Metals (Butterworth, London 1961).

    Google Scholar 

  10. N. S. MacDonald, F. Ezmirlian, P. Spain andC. MacArthur, J. biol. Chem.189, 387 (1951).

    PubMed  Google Scholar 

  11. F. W. Lengemann, Proc. Soc. exp. Biol. Med.94, 64 (1957).

    PubMed  Google Scholar 

  12. A. B. G. Lansdown, Histochemie13, 192 (1968).

    Article  PubMed  Google Scholar 

  13. D. F. Waterhouse, Nature, Lond.167, 358 (1951).

    Google Scholar 

  14. N. S. MacDonald, R. E. Nusbaum, R. Stearns, E. Ezmirlian, C. MacArthur andP. Spain, J. biol. Chem.188, 137 (1951).

    PubMed  Google Scholar 

  15. S. A. Gunn, T. C. Gould andW. A. D. Anderson, J. Reprod. Fert.21, 443 (1970).

    Google Scholar 

  16. S. A. Gunn, T. C. Gould andW. A. D. Anderson, Biol. Reprod.3, 35 (1970).

    PubMed  Google Scholar 

  17. V. Totović, Virchows Arch. path. Anat. Physiol.339, 151 (1965).

    Article  Google Scholar 

  18. J. E. Mulvihill, S. H. Gamm andV. H. Ferm, J. Embryol. exp. Morph.24, 393 (1970).

    PubMed  Google Scholar 

  19. L. A. Muro andR. A. Goyer, Arch. Path.87, 660 (1969).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, England

    A. B. G. Lansdown, R. C. Longland & P. Grasso

Authors
  1. A. B. G. Lansdown
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. C. Longland
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Grasso
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

We are indebted to Mr.K. L. Murray of the Government Chemist's Laboratory for analyzing tissue samples by atomic absorption spectrophotometry. We are also grateful toDr. R. F. Crampton, Director of BIBRA, for his interest and advice in this work.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lansdown, A.B.G., Longland, R.C. & Grasso, P. Reduced foetal calcium without skeletal malformations in rats following high maternal doses of a strontium salt. Experientia 28, 558–560 (1972). https://doi.org/10.1007/BF01931875

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01931875

Keywords

Search

Navigation