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Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice

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Summary

A single injection of cortisone or thyroxine to 8-day-old suckling mice initiates a temporary decrease of lactase activity. On the contrary, 3 injections of cortisone or thyroxine provoke a significant increase of lactase activity. It appears that the mechanism which controls the postnatal development of lactase in suckling animals is more complex than expected.

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Authors and Affiliations

  1. Intestinal Biology Unit, Department of Anatomy and Cell Biology, University of Sherbrooke, J1H 5N4, Sherbrooke, Québec, Canada

    C. Malo & D. Ménard

Authors
  1. C. Malo
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  2. D. Ménard
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Additional information

Supported by grant MA-5969 from the Medical Research Council of Canada to D. M. C. M. is a recipient of a studentship from MRC of Canada.

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Malo, C., Ménard, D. Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice. Experientia 35, 493–494 (1979). https://doi.org/10.1007/BF01922726

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  • DOI: https://doi.org/10.1007/BF01922726

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