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Temperature variation and the function of complement and antibody of amphibia

  • Haematologica, Immunologica
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Summary

Temperature treatment of sera of erythrocyte immunized adults of 3 amphibian species has shown that cooling enhances antigen-antibody complexing and does not alter complement function in vitro. These findings bear on understanding in vivo temperature immunosuppression in poikilotherms.

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This research was partially supported by a grant No. AI-12846 from the National Institutes of Health, Bethesda, Md, USA. The authors are grateful for the technical assistance of Ms J. S. Ruben.

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Ruben, L.N., Edwards, B.F. & Rising, J. Temperature variation and the function of complement and antibody of amphibia. Experientia 33, 1522–1524 (1977). https://doi.org/10.1007/BF01918848

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