Skip to main content
Log in

Assessment of power spectral edge for monitoring depth of anaesthesia using low methohexitone infusion

  • Published:
International journal of clinical monitoring and computing

Summary

The study describes an attempt to determine the minimal sleep infusion rate for the intravenous anaesthetic, methohexitone using EEG power spectral edge (PSE) as an index of anaesthetic depth. PSE was found to remain stable during a continuous infusion at declining rates, with decreasing plasma concentration. We were unable to define a sleep infusion rate using PSE as an index of anaesthetic depth. PSE was found to be unsuitable for monitoring anaesthetic depth.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Eger I, Saidman L, Brandstater B: Minimum alveolar concentrations: a standard of anaesthetic potency. Anesthesiology 26: 756, 1965.

    PubMed  Google Scholar 

  2. Merkel G, Eger I: A comparative study of halothane and halopropane anaesthesia including method for determining equipotency. Anesthesiology 24: 346, 1963.

    Article  PubMed  CAS  Google Scholar 

  3. Prys-Roberts C: Practical and pharmacological implications of continuous intravenous anaesthesia. Acta Anesth Belg 31: 225–230, 1980.

    CAS  Google Scholar 

  4. Sear JW, Prys-Roberts C: Dose related haemodynamic effects of continuous infusion of Althesin in man. Br J Anaesth 51: 867–873, 1979.

    Article  PubMed  CAS  Google Scholar 

  5. Rampil IJ, Sasse FJ, Smith NT, Hoff BH, Flemming DC: Spectral edge frequency — a new correlate of anesthetic depth. ASA Abstracts, Anesthesiology 53, No. 3, Sept. 1980.

  6. Hudson R, Stanski D, Saidman L, Meathe E: A model for studying depth of anaesthesia and acute tolerance to thiopental. Anesthesiology 59: 301–308, 1983.

    Article  PubMed  CAS  Google Scholar 

  7. Scott JC, Ponganis KV, Stanski DR: EEG quantification of narcotic effect: The comparative pharmacodynamics of fentanyl and alfentanil. Anesthesiology 62: 234–241, 1985.

    PubMed  CAS  Google Scholar 

  8. Hudson R, Stanski D, Burch P: Comparative pharmacokinetics of methohexital and thiopentone. Anesthesiology 56: 263–8, 1982.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Withington, P.S., Morton, J., Arnold, R. et al. Assessment of power spectral edge for monitoring depth of anaesthesia using low methohexitone infusion. International Journal of Clinical Monitoring and Computing 3, 117–122 (1986). https://doi.org/10.1007/BF01880764

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01880764

Keywords

Navigation