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Cardiac myxoma

Clinical and pathologic features in 15 cases

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Summary

Neoplasms are rare cardiac findings of which myxomas comprise about 75%. We report of 15 patients, predominantly female (60%) with a mean age of 58.8 years. Male patients (40%) were 20 years younger on average.

80% of these tumors developed in the left atrium fixed to the atrial septum. In 2 patients the right ventricle and in 1 patient the right atrium was involved. No left ventricular or bilateral tumors were found. Clinical findings showed a great variety of symptoms. Often misdiagnosis was established until echocardiography was performed. Major symptoms were dyspnea (80%), elevated erythrocyte sedimentation rate (73%), arrhythmias (53%), lung edema (47%), embolization (40%) and anemia (40%).

Pathological examination and tumor genesis are still in discussion. Several theories are reported in literature: a true thrombus, thrombus organization with malignant potential, true neoplasms as well as a familiar myxoma complex may explain clinical and histological features. Our findings did not confirm only one theory but emphasize different possibilities.

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Abbreviations

LA:

Left atrium

RA:

Right atrium

RV:

Right ventricle

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Schmid, C., Paterakis, S., Likungu, J.A. et al. Cardiac myxoma. Klin Wochenschr 66, 713–717 (1988). https://doi.org/10.1007/BF01726413

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  • DOI: https://doi.org/10.1007/BF01726413

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