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Azole resistance inCandida

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Abstract

Resistance ofCandida to azoles is an increasing problem. Susceptibility testing ofCandida against fluconazole and ketoconazole is now feasible and desirable. Good correlation of resistance in vitro with clinical failure of fluconazole therapy has now been shown in mucosal candidiasis. The relationship, if any, between resistance and clinical failure in the context of invasive candidiasis is not clear at present and additional correlative work needs to be done. Monitoring of resistance trends inCandida is clearly important now.

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  1. Department of Infectious Diseases and Tropical Medicine, Monsall Unit, North Manchester General Hospital, Delaunays Road, M8 6RB, Manchester, UK

    D. W. Denning, G. G. Baily & S. V. Hood

  2. Department of Medicine, Hope Hospital, M6 8HD, Salford, UK

    D. W. Denning

  3. University of Manchester, Manchester, UK

    D. W. Denning

  4. Department of Genitourinary Medicine, St. Bartholomew's Hospital, London, UK

    G. G. Baily

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Denning, D.W., Baily, G.G. & Hood, S.V. Azole resistance inCandida . Eur. J. Clin. Microbiol. Infect. Dis. 16, 261–280 (1997). https://doi.org/10.1007/BF01695630

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