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Comparative study of intestinal disaccharidases in thai and European subjects

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Summary

The activities of three disaccharidases (lactase, saccharase, maltase) and alkaline phosphatase in jejunal biopsies were determined in a group of 24 adult subjects from Northern Thailand and one of 9 Europeans. The mean activities of saccharase, maltase and alkaline phosphatase were similar in both groups. In contrast, a highly significant difference was found between the very low activity of lactase in all Thai subjects and lactase activity in Europeans. There was no difference of the mean activity of the four enzymes studied between Thai subjects with normal (n=8) and slightly altered (n=7) histological picture of the intestinal mucosa.

Zusammenfassung

Die Aktivitäten von 3 Disaccharidasen (Lactase, Saccharase, Maltase) und der alkalischen Phosphatase wurden in Jejunum-Biopsien von 24 Erwachsenen aus Nordthailand und von 9 Europäern bestimmt. Die mittleren Aktivitäten der Saccharase, Maltase und alkalischen Phosphatase waren in beiden Gruppen ähnlich. Im Gegensatz hierzu bestand ein signifikanter Unterschied zwischen den sehr niedrigen Aktivitäten der Lactase bei allen Thai-Versuchspersonen und den Lactase-Aktivitäten bei Europäern. Die mittleren Aktivitäten der vier untersuchten Enzyme unterschieden sich nicht wesentlich beim Vergleich von 8 Thailändern mit normalem und 7 mit leicht verändertem histologischem Bild der intestinalen Mucosa.

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Authors and Affiliations

  1. Universitäts-Kinderklinik Bonn, Germany

    Hans Werner Rotthauwe & Dieter Emons

  2. Department of Medicine, Faculty of Medicine, Chiang Mai University, USA

    Muni Kaeoplung

  3. Department of Pathology, Faculty of Medicine, Chiang Mai University, USA

    Tavipan Tantachamroon & Gebhard Flatz

Authors
  1. Hans Werner Rotthauwe
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  2. Dieter Emons
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  3. Muni Kaeoplung
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  4. Tavipan Tantachamroon
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  5. Gebhard Flatz
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Additional information

Supported by Stiftung Volkswagenwerk.

Supported by Landesamt für Forschung Nordrhein-Westfalen.

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Rotthauwe, H.W., Emons, D., Kaeoplung, M. et al. Comparative study of intestinal disaccharidases in thai and European subjects. Klin Wochenschr 49, 503–504 (1971). https://doi.org/10.1007/BF01485306

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  • DOI: https://doi.org/10.1007/BF01485306

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