Summary
Fourteen patients with NPH were studied with special reference to associated EEG changes, one case being reported in detail. In 13 cases the EEG was abnormal, the abnormality most frequently observed being a of the rhythmic slow wave type, consisting of bursts of monorhythmic theta or delta waves seen in both hemispheres. This type of abnormality was present in 7 cases. In 4 of the 5 cases with serial EEGs the abnormality became more accentuated with the advance of the illness. In 4 of 5 cases in whom postoperative EEGs were obtained there was significant improvement of the EEG after the shunting procedure.
There were strong correlations between the EEG abnormality described, demonstrable ventricular reflux on cisternography, and the effectiveness of the shunt operation.
It was considered that serial EEGs are a useful diagnostic procedure in following up patients at risk of developing NPH.
Similar content being viewed by others
References
Adams, R. D., C. M. Fisher, S. Hakim, R. G. Ojemann, and W. H. Sweet, Symptomatic occult hydrocephalus with “normal” cerebrospinal fluid pressure. A treatable syndrome. New Eng. J. Med.273 (1965), 117–126.
Ohta, T., H. Ueno, H. Handa, and Y. Hamanaka, Eight cases of surgically treated normal pressure hydrocephalus. Brain Nerve (Tokyo)21 (1969), 829–838 (Jap.).
Benini, A., and H. Krayenbühl, Hydrocephalus occultus symptomaticus. Ein klinisch neuartiges Syndrom. Ätiologie, Pathogenese, Diagnose und Therapie. Schweiz. Med. Wschr.99 (1969), 621–630.
Greitz, T. V. B., A. O. L. Grepe, M. S. F. Kalmér, and J. Lopez, Pre- and postoperative evaluation of cerebral blood flow in low pressure hydrocephalus. J. Neurosurg.31 (1969), 644–651.
Brown, D. G., and E. S. Goldensohn, The electroencephalogram in normal pressure hydrocephalus. Arch. Neurol.29 (1973), 70–71.
Hogan, P. A., and R. M. Woolsey, Hydrocephalus in the adult. JAMA198 (1966), 524–528.
McHugh, R. R., Occult hydrocephalus. Quart. J. Med.33 (1964), 297–308.
Messert, B., T. K. Henke, and W. Langheim, Syndrome of akinetic mutism associated with obstructive hydrocephalus. Neurology (Minneap.)16 (1966), 635–649.
Daly, D., J. L. Whelan, R. G. Bickford, and C. S. MacCarty, The electroencephalogram in cases of tumors of the posterior fossa and third ventricle. Electroencephalogr. Clin. Neurophysiol.5 (1953), 203–216.
Cordeau, J. P., Monorhythmic frontal delta activity in the human electroencephalogram: A study of 100 cases. Electroencephalogr. Clin. Neurophysiol.11 (1959), 733–749.
Bagchi, B., K. A. Kooi, B. T. Selving, and H. D. Calhoun, Subtentorial tumors and other lesions: An electroencephalographic study of 121 cases. Electroencephalogr. Clin. Neurophysiol.13 (1961), 180–192.
Van der Drift, J. H., and O. Magnus, Primary thalamic lesions. Electroencephalogr. Clin. Neurophysiol. (Suppl.)19 (1961), 125–137.
Nakai, O., Clinical electroencephalography in cases of deep subcortical and infratentorial tumours. Prog. Nerv. Res. (Tokyo)5 (1961), 154–177 (Jap.).
Dyken, P., H. L. Manning, and P. White, Electroencephalographic changes associated with cerebellar hemisphere tumors. J. Neurol. Neurosurg. Psychiat.27 (1964), 340–344.
Wilson, W. P., G. T. Tindall, and J. C. Greenfield, Jr., Effects of an acute increase of intracranial pressure upon the electroencephalogram. Electroencephalogr. Clin. Neurophysiol.19 (1965), 184–186.
Notermans, S. L. H., and S. Boonstra, Electroencephalographic findings in experimentally induced intracranial hypertension. Electroencephalogr. Clin. Neurophysiol.21 (1969), 337–345.
Hakim, S., and R. D. Adams, The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure: Observations on cerebrospinal fluid hydrodynamics. J. Neurol. Sci.2 (1965), 307–327.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hashi, K., Nishimura, S., Kondo, A. et al. The EEG in normal pressure hydrocephalus. Acta neurochir 33, 23–35 (1976). https://doi.org/10.1007/BF01405738
Issue Date:
DOI: https://doi.org/10.1007/BF01405738