Zusammenfassung
Bei einem 4 Monate alten Kind mit serologischem Nachweis für Rötelnembryopathie und positiver Viruskultur werden die histologischen Veränderungen des Felsenbeins beschrieben und diskutiert. Die primären Schäden waren bei diesem Fall in der Stria vascularis, in der Membrana tectoria, in den Haarzellen des Cortischen Organs und im Sacculus lokalisiert. Sie waren ähnlich der sog. Cochleo-sacculären Degeneration vom Typ Scheibe und entsprachen auch den Veränderungen, wie sie bei postnatalen Masern beschrieben worden sind.
Darüber hinaus worden folgende pathologischen Befunde bei diesem Fall beobachtet:
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1.
Eine typische Verteilung von Haarzelldegenerationen in der Cochlea.
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2.
Eosinophiles Material in den Perilymphräumen, meist offenbar als Ausschwitzung von den Gefäßen der Scala tympani.
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3.
Formveränderung der zweiten Schneckenwindung und des Rosenthalschen Kanals und
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4.
Anomalie des Steigbügels.
Summary
The histopathological abnormalities in the temporal bone of a four-month-old infant with positive virus culture and serological data for maternal rubella are presented and discussed.
The primary abnormalities of this case were located in the stria vascularis, tectorial membrane, hair cells in Corti's organ and the Sacculus, and similar to the so-called cochleo-saccular degeneration of Scheibe and also those observed in postnatal measles.
Additional pathological findings observed in this case were:
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1.
the specific distribution of the severely-degenerated hair cells in the cochlea,
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2.
the eosinophilic material in the perilymphatic space most likely coming from vessels in the scala tympani,
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3.
the slight distortion of the cochlear second turn and Rosenthal's canal, and
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4.
the stapes anomalies.
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This study was supported by a Deafness Research Foundation Grant. No. 67 207.
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Hemenway, W.G., Sando, I. & McChesney, D. Temporal bone pathology following maternal rubella. Arch. Klin. Exp. Ohr.-, Nas.- U. Kehlk. Heilk. 193, 287–300 (1969). https://doi.org/10.1007/BF01368091
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DOI: https://doi.org/10.1007/BF01368091