Summary
Avian infectious bronchitis virus Beaudette-42 strain showed antigenic variation during serial passages in BHK-21 cells. The same strain serial passaged in chicken cells or five times in the presence of antibody did not change its antigenicity.
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Otsuki, K., Tagawa, Y. & Tsubokura, M. Antigenic variation of avian infectious bronchitis virus during replication in BHK-21 cells. Archives of Virology 73, 75–78 (1982). https://doi.org/10.1007/BF01341730
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DOI: https://doi.org/10.1007/BF01341730