Abstract
The present paper evaluates the efficiency of Nissen fundoplication as an antireflux technique in a series of 51 patients with different grades of esophagitis. Follow-up time averaged 6.6 years. The evaluation includes a clinical assessment, endoscopic study, and 24-hr pH monitoring. The results reveal an acceptable rate of recurrences, with clinical (9.8%) being less frequent than endoscopic (13.7%) or pH-metric (19.6%) recurrences. Side effects appeared in 37.3% of the patients (mainly inability to belch or vomit, and postprandial fullness), which were mild and transitory in most cases. Nissen fundoplication proved effective in controlling long-term gastroesophageal reflux, as over 80% of the patients presented an excellent-to-good clinical situation, without or with minimal digestive consequences.
Similar content being viewed by others
References
Brand DL, Eastwood IR, Martin D, Carter WB, Pope CE: Esophagus symptoms, manometry and histology before and after surgery: A long-term follow-up study. Gastroenterology 76:1393, 1979
Negre JB: Post-funduolication symptoms: do they restrict the success of Nissen fundoplication? Ann Surg 198:698–700, 1983
Polk HC Jr: Indication for, technique of, and results of fundoplication for complicated reflux esophagitis. Am Surg 44:620–627, 1978
Negre JP, Markkula HT, Kerylainen O: Nissen fundoplication: Results at 10-year follow-up. Am J Surg 146:635–641, 1983
DeMeester TR, Johnson LF, Kent AH: Evaluation of current operations for the prevention of gastroesophageal reflux. Ann Surg 180:511–516, 1974
Ellis FH, Crozier RE: Reflux, control by fundoplication: a clinical and manometric assessment of the Nissen operation. Ann Thorac Surg 38:387–389, 1984
Bancewick J, Mughal M, Marples M: The lower oesophageal sphincter after floppy Nissen fundoplication. Br J Surg 74:162–164, 1987
DeMeester TR, Bonavina L, Albertucci M: Nissen fundoplication for gastroesophageal reflux disease. Evaluation of primary repair in 100 consecutive patients. Ann Surg 204:9–20, 1986
Woodward ER, Thomas HF, McCalhany JC: Comparison of crural repair and Nissen fundoplication in the treatment of esophageal hiatus hernia with peptic esophatitis. Ann Surg 173:682–692, 1971
O'Hanrahan T, Marples M, Bancewicz J: Recurrent reflux and wrap disruption after Nissen fundoplication Detection, incidence and timing. Br J Surg 77:545–547, 1990
Stipa S, Fegiz G, Iascone C, Paolini A, Moraldi A, De Marchi C, Chieco PA: Belsey and Nissen operations for gastroesophageal reflux. Ann Surg 210:583–589, 1989
Savary M, Miller G: The esophagus.In Handbook and Atlas of Endoscopy. Gassman, Solothurn, 1977
Johnson LF, DeMeester TR: Development of the 24-hour intraesophageal pH monitoring composite scoring system. J Clin Gastroenterol 8(suppl. 1):52–58, 1986
Donahue PE, Samelson S, Nyhus LM, Bombeck CT: The floppy Nissen fundoplication. Effective long-term control of pathologic reflux. Arch Surg 120:663–668, 1985
Rossman F, Brantigan CO, Sawyer RB: Obstructive complication of the Nissen fundoplication. Am Surg 42:821–826, 1976
Bushkin FL, Neustein CL, Parker TH, Woodward ER: Nissen fundoplication for reflux peptic esophagitis. Ann Surg 185:672–675, 1977
Shirazi SS, Schulze K, Soper RT: Long-term follow-up for treatment of complicated chronic reflux esophagitis. Arch Surg 122:548–582, 1987
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Martinez De Haro, L.F., Ortiz, A., Parrilla, P. et al. Long-term results of nissen fundoplication in reflux esophagitis without strictures. Digest Dis Sci 37, 523–527 (1992). https://doi.org/10.1007/BF01307574
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01307574