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High mutation rate of foot-and-mouth disease virus treated with hydroxylamine

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Summary

It was found experimentally that 39% of the surviving plaque-forming units are mutants when the total infectivity of the treated sample is decreased by one neperian logarithm through inactivation with hydroxylamine.

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Author notes

  1. R. Maes

    Present address: Centro Pan-Americano de Febre Aftosa, Organização Pan Americana da Saúde, Caixa Postal 589, ZC-00, Rio de Janeiro, Brasil

  2. J. Mesquita

    Present address: Departamento de Ciências Biológicas, Escola Nacional des Saúde Pública, Caixa Postal 16, ZC-24, Rio de Janeiro, Brasil

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    1. R. Maes
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    2. J. Mesquita
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    Maes, R., Mesquita, J. High mutation rate of foot-and-mouth disease virus treated with hydroxylamine. Archiv f Virusforschung 29, 77–82 (1970). https://doi.org/10.1007/BF01253882

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    • DOI: https://doi.org/10.1007/BF01253882

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