Abstract
The halogenation of imperialine has given 3α-chloroimperialine, 3β-chloroimperialine, 3α, 6, 6-trichloroimperialine, and 3β-bromoimperialine. 3β-Chloroimperialine was identical with a known chloroimperialine. The structures of the new compounds have been established. Their muscarinolytic activities have been determined.
Similar content being viewed by others
References
Yu. R. Mirzaev, Dokl. Akad. Nauk UzSSR, No. 6, 48 (1988).
Yu. R. Mirzaev, R. Shakirov, U. T. Shakirova, and A. Nabiev, Khim. Prir. Soedin., 587 (1993).
R. N. Nuriddinov and S. Yu. Unusov, Dokl. Akad. Nauk UzSSR, No. 4, 33 (1961).
S. Ito, Y. Fukasawa, and M. Miyashita, Tetrahedron Lea.,36, 3161 (1976).
R. Shakirov and S. Yu. Yunusov, Khim. Prir. Soedin., 3 (1980).
T. T. Chu and J. Y. Loh, Acta China. Sinica,22, 365 (1956); Chem. Abs.51, 445 (1957).
R. N. Nuriddinov and S. Yu. Yunusov, Khim. Prir. Soedin., 260 (1968).
K. Kaneko, N. Naruso, K. Haruki, and H. Mitsuhashi, Chem. Pharm. Bull,28, 1345 (1980).
Additional information
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Original article submitted November 7, 1994. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 269–271, March–April, 1995. Original article submitted November 7, 1994.
Rights and permissions
About this article
Cite this article
Shakirova, U.T., Shakirov, R. & Mirzaev, Y.R. Halogen derivatives of imperialine and their muscarinolytic activity. Chem Nat Compd 31, 221–223 (1995). https://doi.org/10.1007/BF01170210
Issue Date:
DOI: https://doi.org/10.1007/BF01170210