Summary
The potential of chlorophyllin in reducing clastogenicity was studied against two concentrations of each of three potent metallic clastogens (cesium chloride, mercuric chloride and cobalt chloride) in bone marrow cells of mice in vivo. The respective salts and chlorophyllin were administered orally to mice by gavaging in different combinations. Simultaneous administration of chlorophyllin with both concentrations of each salt reduced the clastogenic effects in the order Cs > Hg > Co. Chlorophyllin could not decrease the clastogenic effects when administered 2 h before the salts.
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Ghosh, A.K., Sen, S., Palit, S. et al. Comparative efficacy of chlorophyllin in reducing cytotoxicity of some heavy metals. Biol Metals 4, 158–161 (1991). https://doi.org/10.1007/BF01141307
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DOI: https://doi.org/10.1007/BF01141307