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Conversion ofN-acetyl-o-toluidine into 4′-hydroxy-N-acetyl-o-toluidine byFusarium verticillioides

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Summary

Approximately 850 fungus and yeast strains were tested for their ability to hydroxylateN-acetyl-o-toluidine in the 4′-position. The strain Y-1 selected as the best producer, was identified asFusarium verticilliides, and accumulated 1.5 mg of 4′-hydroxy-N-acetyl-o-toluidine per ml of culture broth.

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Authors and Affiliations

  1. Department of Agricultural Chemistry, Kyoto University, Kitashirakawa, Oiwake-cho, Sakyo-ku, 606, Kyoto, Japan

    Toru Nagasawa & Hideaki Yamada

  2. Nippon Kayaku Co., Ltd., 31-12 Shimo 3-chome, Kita-ku, 115, Tokyo, Japan

    Hideki Yoshioka & Ryoichi Hasegawa

Authors
  1. Hideki Yoshioka
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  2. Toru Nagasawa
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  3. Ryoichi Hasegawa
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  4. Hideaki Yamada
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Yoshioka, H., Nagasawa, T., Hasegawa, R. et al. Conversion ofN-acetyl-o-toluidine into 4′-hydroxy-N-acetyl-o-toluidine byFusarium verticillioides . Biotechnol Lett 12, 679–684 (1990). https://doi.org/10.1007/BF01088193

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  • DOI: https://doi.org/10.1007/BF01088193

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