Abstract
During a two-week period 54 ward personnel were exposed to two patients with severe type B hepatitis. No specific isolation precautions were used other than separate collection of hypodermic needles. During a 22-week follow-up period, there was no evidence of either overt or subclinical hepatitis in development of hepatitis B surface antigen or antibody to the surface antigen that could be attributed to exposure to the patients. This data does not support requirements for cumbersome and complicated isolation procedures during the care of patients with type B hepatitis.
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Conrad ME: Endemic viral hepatitis in U.S. soldiers: Causative factors and the effect of prophylactic gamma globulin. CMA J 106:456–460, 1972
Krugman S, Giles JP, Hammond J: Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection. JAMA 200:365–373, 1967
Szmuness W, Prince AM, Hirsch RL, Brotman B: Familial clustering of hepatitis B infection. N Engl J Med 289:1162–1166, 1973
Heathcote J, Cameron CH, Dane DS: Hepatitis-B antigen in saliva and semen. Lancet 1:71–73, 1974
Ward R, Borchert P, Wright A, Kline E: Hepatitis B antigen in saliva and mouth washings. Lancet 2:726–727, 1972
Villarejos VM, Visona KA, Gutierrez A, Rodriguez A: Role of saliva, urine and feces in the transmission of type B hepatitis. N. Engl J Med 291:1375–1378, 1974
Heathcote J, Tsianides A, Sherlock S: A urinary substance in patients with acute type-B hepatitis and their household contacts. Lancet 2:593–595, 1973
Hersh T, Melnick JL, Goyal RK, Hollinger FB: Non-parenteral transmission of viral hepatitis type B (Australia antigen-associated serum hepatitis). N Engl J Med 285:1363–1364, 1971
Walsh JH, Yalow R, Berson SA: Detection of Australia antigen and antibody by means of radioimmunoassay techniques. J Infect Dis 121:550–554, 1970
Cherubin CE, Purcell RH, Lander JJ, McGinn TG, Cone LA: Acquisition of antibody to hepatitis B antigen in three socioeconomically different medical populations. Lancet 2:149–151, 1972
Prince A, Brotman B, Cherubin C: Immune response in patients who received blood containing serum hepatitis antigen. Am J Dis Child 123:415–418, 1972
Swartzberg J, Kern F Jr: Hepatitis B antibody, JAMA 224:527, 1973
Barker LF, Peterson MR, Shulman NR, Murray R: Antibody responses in viral hepatitis, type B. JAMA 223:1005–1008, 1973
Reed WD, Mitchell CG, Eddleston ALWF, Lee WM, Williams R, Zuckerman AJ: Exposure and immunity to hepatitis B virus in a liver unit. Lancet 1:581–583, 1974
Bryan JA, Carr HE, Gregg MB: An outbreak of nonparenterally transmitted hepatitis B. JAMA 223:279–283, 1973
Garibaldi RA, Hatch FE, Bisno AL, Hatch MH, Gregg MB: Nonparenteral serum hepatitis. Report of an outbreak. JAMA 220:963–966, 1972
Garibaldi RA, Rasmussen CM, Holmes AW, Gregg MB: Hospital-acquired serum hepatitis. Report of an outbreak. JAMA 219:1577–1580, 1972
Rosenberg JL, Jones DP, Lipitz LR, Kirsner JB: Viral hepatitis: An occupational hazard to surgeons. JAMA 223:395–400, 1973
Bentley P, Haynes D, Sharpstone P, Taylor PE: Screening for transmission of hepatitis within a liver unit. J Hyg (Camb) 70:197–202, 1972
Isolation Techniques for Use in Hospitals. DHEW Publication (CDC) 76-8314, U.S. Government Printing Office, Washington, D.C. 2nd Ed., 1975.
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Wickliffe, C.W., Galambos, J.T., Rivers, S. et al. The risk of hepatitis B to hospital personnel. Digest Dis Sci 23, 293–296 (1978). https://doi.org/10.1007/BF01072408
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DOI: https://doi.org/10.1007/BF01072408