Skip to main content
SpringerLink
Log in

Morphine preference of alcohol-avoiding and alcohol-preferring C57BL mice

  • Published:
Behavior Genetics Aims and scope Submit manuscript

Abstract

C57BL/Uae inbred mice are similar to C57BL/6J and C57BL/10J mice in displaying a high preference for morphine presented in a saccharin vehicle. C57BL/Uae mice are unique among investigated C57BL lines in not showing a high preference for alcohol. This pattern of differences among closely related inbred strains could be useful in investigating commonalities of alcohol and morphine effects.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Blum, D., Wallace, J. E., Schwerter, H. A., and Eubanks, J. D. (1976). Morphine suppression of ethanol withdrawal in mice.Experientia 32:79–82.

    Google Scholar 

  • Davis, V. E., and Walsh, M. J. (1970). Alcohol, amines and alkaloids: A possible biochemical basis for alcohol addiction.Science 167:1005–1007.

    Google Scholar 

  • Horowitz, G. P. (1976). Morphine self-administration by inbred mice: A preliminary report.Behav. Genet. 6:109–110 (abst.).

    Google Scholar 

  • Horowitz, G. P., and Whitney, G. (1975). Alcohol-induced conditioned aversion: Genotypic specificity in mice (Mus musculus).J. Comp. Physiol. Psychol. 89:340–346.

    Google Scholar 

  • Horowitz, G. P., Whitney, G., Smith, J. C., and Stephan, F. K. (1977). Morphine ingestion: Genetic control in mice.Psychopharmacology 52:119–122.

    Google Scholar 

  • McClearn, G. E., and Rodgers, D. A. (1959). Differences in alcohol preference among inbred strains of mice.Quart. J. Stud. Alc. 20:691–695.

    Google Scholar 

  • Nichols, J. R. (1972). Alcoholism and opiate addiction: Theory and evidence for a genetic link between the two. In Forsander, O., and Eriksson, K. (eds.),Biological Aspects of Alcohol Consumption, Finnish Foundation for Alcohol Studies, Helsinki.

    Google Scholar 

  • Poley, W. (1972). Alcohol-preferring and alcohol-avoiding C57BL mice.Behav. Genet. 2:245–248.

    Google Scholar 

  • Rodgers, D. A. (1966). Factors underlying differences in alcohol preference among inbred strains of mice.Psychosom. Med. 28:498–513.

    Google Scholar 

  • Whitney, G., McClearn, G. E., and DeFries, J. C. (1970). Heritability of alcohol preference in laboratory mice and rats.J. Hered. 61:165–169.

    Google Scholar 

  • Whitney, G., Horowitz, G. P., and Collins, R. L. (1977). Relationship between morphine self-administration and the effect of morphine across strains of mice.Behav. Genet. 7:92 (abst.).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychology, Florida State University, 32306, Tallahassee, Florida

    Glayde Whitney & Gary P. Horowitz

Authors
  1. Glayde Whitney
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gary P. Horowitz
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported by NIDA Grant No. 00828 and NIMH Grant No. 11218.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Whitney, G., Horowitz, G.P. Morphine preference of alcohol-avoiding and alcohol-preferring C57BL mice. Behav Genet 8, 177–182 (1978). https://doi.org/10.1007/BF01066874

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01066874

Key Words

Search

Navigation