Abstract
The functional organization of the primary olfactory center of the frog was investigated. The dynamics of changes in individual components of the potential evoked by electrical stimulation of the olfactory nerve corresponds to morphological evidence of the asymmetrical structure of the frog olfactory bulb. The character of spatial localization and of the properties of individual components of the orthodromically evoked potential suggests that a monosynaptic reciprocal activating system participates in the production of the main component of the response. The similarity between the durations of the inhibitory pauses in spontaneous activity of the mitral cells during stimulation of the olfactory nerves and of the lateral olfactory tract indicates that when all these methods of stimulation are used a single system controlling excitability of the secondary neurons is activated. It is postulated that inhibition of the mitral cells is evoked as a result of activation of a polysynaptic recurrent system incorporating interneurons.
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Literature cited
G. S. Voronkov, Data on the Structural and Functional Organization of the Frog Olfactory Bulb. Author's Abstract of Candidate's Dissertation [in Russian], Moscow (1969).
K. G. Gusel'nikova and G. S. Voronkov, "The orthodromic potential and evoked rhythmic activity in the frog olfactory bulb," Biol. Nauki,4, 101 (1966).
K. G. Gusel'nikova, G. S. Voronkov, L. E. Tsitolovskii, and V. V. Éngovatov, "Nature of the principal components of the orthodromic potential and inhibition of secondary neurons of the frog olfactory bulb," Zh. Vyssh. Nervn. Deyat.,20, 649 (1970).
S. É. Margolis, "The principal component of the evoked potentials of the frog olfactory lobes," Dokl. Akad. Nauk SSSR,190, 729 (1970).
S. É. Margolis, "Evoked potentials of the frog's olfactory lobes in response to electrical stimulation of the olfactory nerve," in: A. I. Karamyan (editor), Electrophysiological Investigations of the Vertebrate Central Nervous System [in Russian], Nauka, Leningrad (1970), pp. 182–190.
S. É. Margolis, "On some properties of the antidromically evoked potential of the frog olfactory bulb," Zh. Évolyuts. Biokhim. i Fiziol.,7, 169 (1971).
S. É. Margolis, "Some features of similarity in the organization of the primary olfactory center in various vertebrates," Abstracts of Proceedings of an All-Union Conference in Memory of Kh. S. Koshtoyants [in Russian], Erevan (1971), pp. 76–77.
A. V. Minor, G. I. Flerova, and A. L. Byzov, "Integral evoked potentials and single unit activity in the frog olfactory bulb," Neirofiziologiya,1, 269 (1969).
R. A. Nicoll, "Inhibitory mechanisms in the rabbit olfactory bulb: dendro-dendritic mechanisms," Brain Res.,14, 157 (1969).
D. Ottoson, "Olfactory bulb potentials induced by electrical stimulation of the nasal mucosa in the frog," Acta Physiol. Scand.,47, 160 (1959).
C. G. Phillips, T. P. Powell, and G. M. Shepherd, "Responses of mitral cells to stimulation of the lateral olfactory tract in the rabbit," J. Physiol. (London),168, 65 (1963).
W. Rall and G. M. Shepherd, "Theoretical reconstruction of field potentials and dendro-dendritic synaptic interactions in olfactory bulb," J. Neurophysiol.,31, 884 (1968).
G. M. Shepherd, "Responses of mitral cells to olfactory nerve volleys in the rabbit," J. Physiol. (London),168, 89 (1963).
G. M. Shepherd, "Neuronal systems controlling mitral cell excitability," J. Physiol. (London),168, 101 (1963).
Additional information
A. N. Severtsov Institute of Evolutionary Morphology and Ecology of Animals, Academy of Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 4, No. 2, pp. 184–191, March–April, 1972.
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Margolis, S.É. Origin of orthodromic evoked potential in the frog olfactory bulb. Neurophysiology 4, 139–144 (1972). https://doi.org/10.1007/BF01063419
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DOI: https://doi.org/10.1007/BF01063419