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First experimental study of carbon dioxide digital subtraction lymphangiography

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Abstract

Fourteen pigs with an average weight of 17 kg were used in this study. Under general anesthesia and magnification 1–3 ccm/kg of carbon dioxide were administered in the lymph vessels of the front and rear legs. Imaging of the peripheral lymph vessels, lymph nodes and the thoracic duct was achieved with digital subtraction angiography. The quality of lymphangiography was satisfactory and comparable with that of the standard non-ionic contrast agent. It is anticipated that further technical evolution will permit the application of CO2/DSA lymphangiography to man. Carbon dioxide is non-nephrotoxic and is non-allergic; it is inexpensive, can be administered in unlimited quantity and is quickly eliminated via the pulmonary system.

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Authors and Affiliations

  1. Vascular Department of the 2nd Surgical Clinic, Medical School, University of Athens, Athens, Greece

    P. B. Dimakakos & M. Papasavval

  2. X-Ray Department, Medical School, University of Athens, Athens, Greece

    T. Stefanopoulos & D. Mourikis

  3. Experimental Department, Medical School, University of Athens, Athens, Greece

    G. Kostopanagiotou

  4. The Anesthesiological Department, Medical School, University of Athens, Athens, Greece

    A. Doufas

Authors
  1. P. B. Dimakakos
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  2. M. Papasavval
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  3. T. Stefanopoulos
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  4. D. Mourikis
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  5. G. Kostopanagiotou
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  6. A. Doufas
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Dimakakos, P.B., Papasavval, M., Stefanopoulos, T. et al. First experimental study of carbon dioxide digital subtraction lymphangiography. Eur J Plast Surg 20, 132–135 (1997). https://doi.org/10.1007/BF01002046

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  • DOI: https://doi.org/10.1007/BF01002046

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