Skip to main content
Log in

Pediatric AIDS

Neuroradiologic and neurodevelopmental findings

  • Originals
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

A group of 23 pediatric patients seropositive for HIV antibody were studied by computed tomography and evaluated neurodevelopmentally. Significant neurodevelopmental delays were found in over 95% of the patients studied. CT findings in six patients were normal and thirteen of 23 (57%) had prominence of the CSF spaces. Less frequent findings included calcifications in the basal ganglia and white matter. Cerebral mass lesions included one case of lymphoma and one case of hemorrhage. The CT findings in the pediatric age group differs from the adult population in that contrast enhancing inflammatory mass lesions are uncommon.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Navia BA, Jordan BD, Price RW (1986) The AIDS dementia complex: I. Clinical features. Ann Neurol 19: 517–524

    Google Scholar 

  2. Farmer TW (1983) Pediatric Neurology. Third edition. Harper and Row, p 173

  3. Shaw GM Harper ME, Hahn BH, et al. (1985) HTLV-III infection in brains of children and adults with AIDS encephalopathy. Science 227: 177–181

    Google Scholar 

  4. Ho DD, Rota TR, Schooley RT, et al. (1985) Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. NEJM 313: 1493–1497

    Google Scholar 

  5. Belman AL, Ultmann MH, Horoupian D, Novick B, Spiro AJ, Rubinstein A, Kurtzberg D, Cone-Wesson B (1985) Neurological complications in infants and children with acquired immune deficiency syndrome. Ann Neurol 18: 560–566

    Google Scholar 

  6. Levy RM, Rosenbloom S, Perrett LV (1986) Neuroradiologic findings in AIDS: a review of 200 cases. AJR 147: 977–983

    Google Scholar 

  7. Sharer LR, Epstein LG, Cho E, Joshi VV, Meyenhofer MF, Rankin LF, Petito CK (1986) Pathologic features of AIDS encephalopathy in children: Evidence for LAV/HTLV-III infection of brain. Human Pathol 17: 271–284

    Google Scholar 

  8. Epstein LG, Sharer LR, Joshi VV, Fojas MM, Koenigsberger MR, Oleske JM (1985) Progressive encephalopathy in children with acquired immune deficiency syndrome. Ann Neurol 17: 488–496

    Google Scholar 

  9. Navia BA, Cho E-S, Petito CK, Price RW (1986) The AIDS dementia complex: II. Neuropathology. Ann Neurol 19: 525–535

    Google Scholar 

  10. Post MJD, Hensley GT, Moskowitz LB, Fischl M (1986) Cytomegalic inclusion virus encephalitis in patients with AIDS: CT, clinical and pathologic correlation. AJR 146: 1229–1234

    Google Scholar 

  11. Ultmann MH, Belman AL, Ruff HA, Novick BE, Cone-Wesson B, Cohen HJ, Rubinstein A (1985) Developmental abnormalities in infants and children with acquired immune deficiency snydrome (AIDS) and AIDS-related complex. Dev Med Child Neurol 27: 563–571

    Google Scholar 

  12. Pahwa S, Kaplan M, Fikrig S, Pahwa R, Sarngadharan MG, Popovic M, Gallo RC (1986) Spectrum of human T-cell lymphotropic virus type III infection in children. JAMA 255: 2299–2303

    Google Scholar 

  13. Lantos G, Belman AL, Dickson D, Horoupian DS, Novick B, Rubinstein A (1986) Brain CT in pediatric patients with Acquired Immunodeficiency Syndrome. Presented at seventy-second annual meeting of the Radiologic Society of North America, November 1986 (Abstract)

  14. Weitzner I, Tenner M, Kairam R, Kaul A, D'Souza L (1986) Brain CT in Congenital AIDS. Presented at the meeting of the American Society of Neuroradiology, January 1986 (Abstract)

  15. Belman AL, Lantos G, Houroupian D, Novick BE, Ultmann MH, Dickson DW, Rubinstein A (1986) AIDS: Calcification of the basal ganglia in infants and children. Neurology 36: 1192–1199

    Google Scholar 

  16. Kleinman PK, Zito JL, Davidson RI, Raptopuolos V (1983) The subarachnoid spaces in children: normal variations in size. Radiology 147: 455–457

    Google Scholar 

  17. Chapter 6 (1985) Hydrocephalus and Atrophy. Victor M. Haughton. In: Williams AL, Haughton VM (eds) Cranial computed tomography. C. V. Mosby, St. Louis, p 250

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Price, D.B., Inglese, C.M., Jacobs, J. et al. Pediatric AIDS. Pediatr Radiol 18, 445–448 (1988). https://doi.org/10.1007/BF00974074

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00974074

Keywords

Navigation