Skip to main content
Log in

C9 deficiency in a patient with poststreptococcal glomerulonephritis

  • Brief Report
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract

The case of a 10-year-old girl with congenital C9 deficiency and poststreptococcal glomerulonephritis (PSGN) is presented. Although her clinical symptoms mimicked those of Henoch-Schönlein purpura, histological examination of a renal biopsy specimen revealed the features commonly described in PSGN.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Fukumori Y, Yoshimura S, Ohnoki S, Yamaguchi H, Akagaki Y, Inai S (1989) A high incidence of C9 deficiency among healthy blood donors in Osaka, Japan. Int Immunol 1: 85–89

    Google Scholar 

  2. Fine DP, Gewurtz H, Lint TF (1983) Meningococcal meningitis in a woman with inherited deficiency of the ninth component of complement. Clin Immunol Immunopathol 28: 413–417

    Google Scholar 

  3. Nagata H, Hara T, Aoki T, Mizuno Y, Akeda H, Inaba S, Tsumoto K, Ueda K (1989) Inherited deficiency of ninth component of complement: an increased risk of meningococcal meningitis. J Pediatr 114: 260–264

    Google Scholar 

  4. Kawai T, Katoh K, Narita M, Tani K, Okubo T (1989) Deficiency of the 9th component of complement (C9) in a patient with systemic lupus erythematosus. J Rheumatol 16: 542–543

    Google Scholar 

  5. Yoshioka K, Takemura T, Akano N, Okada M, Yagi K, Maki S, Inai S, Akita H, Koitabashi Y (1992) IgA nephropathy in patients with congenital C9 deficiency. Kidney Int 42: 1253–1258

    Google Scholar 

  6. Goodyer PR, Chadarevian JP, Kaplan BS (1978) Acute poststreptococcal glomerulonephritis mimicking Henoch-Schönlein purpura. J Pediatr 93: 412–415

    Google Scholar 

  7. Urizar RE, Singh JK, Muhammad T, Hines O (1978) Henoch-Schönlein anaphylactoid purpura nephropathy: electron microscopic lesions mimicking acute poststreptococcal nephritis. Hum Pathol 9: 223–229

    Google Scholar 

  8. Kim CK, Aikawa M, Makker SP (1979) Electron-dense subepithelial glomerular deposits in Henoch-Schönlein purpura syndrome. Arch Pathol Lab Med 103: 595–598

    Google Scholar 

  9. Yoshikawa N, White RHR, Cameron AH (1981) Prognostic significance of the glomerular changes in Henoch-Schönlein purpura nephritis. Clin Nephrol 16: 223–229

    Google Scholar 

  10. Kitamura H, Nagaki K, Inai S (1981) Further study on C9 deficiency. J Clin Lab Immunol 6: 7–11

    Google Scholar 

  11. Lint TF, Zeitz NJ, Gewurtz H (1980) Inherited deficiency of the ninth component in man. J Immunol 125: 2252–2257

    Google Scholar 

  12. Pramoonjago P, Kinoshita T, Hong K, Takatakozono Y, Kozono H, Inagi R, Inoue K (1992) Bactericidal activity of C9-deficient human serum. J Immunol 148: 837–843

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Maruyama, K., Arai, H., Ogawa, T. et al. C9 deficiency in a patient with poststreptococcal glomerulonephritis. Pediatr Nephrol 9, 746–748 (1995). https://doi.org/10.1007/BF00868729

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00868729

Key words

Navigation