Abstract
The case of a 10-year-old girl with congenital C9 deficiency and poststreptococcal glomerulonephritis (PSGN) is presented. Although her clinical symptoms mimicked those of Henoch-Schönlein purpura, histological examination of a renal biopsy specimen revealed the features commonly described in PSGN.
References
Fukumori Y, Yoshimura S, Ohnoki S, Yamaguchi H, Akagaki Y, Inai S (1989) A high incidence of C9 deficiency among healthy blood donors in Osaka, Japan. Int Immunol 1: 85–89
Fine DP, Gewurtz H, Lint TF (1983) Meningococcal meningitis in a woman with inherited deficiency of the ninth component of complement. Clin Immunol Immunopathol 28: 413–417
Nagata H, Hara T, Aoki T, Mizuno Y, Akeda H, Inaba S, Tsumoto K, Ueda K (1989) Inherited deficiency of ninth component of complement: an increased risk of meningococcal meningitis. J Pediatr 114: 260–264
Kawai T, Katoh K, Narita M, Tani K, Okubo T (1989) Deficiency of the 9th component of complement (C9) in a patient with systemic lupus erythematosus. J Rheumatol 16: 542–543
Yoshioka K, Takemura T, Akano N, Okada M, Yagi K, Maki S, Inai S, Akita H, Koitabashi Y (1992) IgA nephropathy in patients with congenital C9 deficiency. Kidney Int 42: 1253–1258
Goodyer PR, Chadarevian JP, Kaplan BS (1978) Acute poststreptococcal glomerulonephritis mimicking Henoch-Schönlein purpura. J Pediatr 93: 412–415
Urizar RE, Singh JK, Muhammad T, Hines O (1978) Henoch-Schönlein anaphylactoid purpura nephropathy: electron microscopic lesions mimicking acute poststreptococcal nephritis. Hum Pathol 9: 223–229
Kim CK, Aikawa M, Makker SP (1979) Electron-dense subepithelial glomerular deposits in Henoch-Schönlein purpura syndrome. Arch Pathol Lab Med 103: 595–598
Yoshikawa N, White RHR, Cameron AH (1981) Prognostic significance of the glomerular changes in Henoch-Schönlein purpura nephritis. Clin Nephrol 16: 223–229
Kitamura H, Nagaki K, Inai S (1981) Further study on C9 deficiency. J Clin Lab Immunol 6: 7–11
Lint TF, Zeitz NJ, Gewurtz H (1980) Inherited deficiency of the ninth component in man. J Immunol 125: 2252–2257
Pramoonjago P, Kinoshita T, Hong K, Takatakozono Y, Kozono H, Inagi R, Inoue K (1992) Bactericidal activity of C9-deficient human serum. J Immunol 148: 837–843
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Maruyama, K., Arai, H., Ogawa, T. et al. C9 deficiency in a patient with poststreptococcal glomerulonephritis. Pediatr Nephrol 9, 746–748 (1995). https://doi.org/10.1007/BF00868729
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00868729