Summary
The generalogical relationships of photoreceptor cells within the compound eye ofDrosophila have been studied using cell labelling, with either3H-thymidine or recessive mutations, during the third larval stage. It has been found that photoreceptor and secondary pigment cells arise from different precursor cells. Under the present experimental conditions, precursors of receptor cells give rise to about 8 elements which differentiate as R cells of two different groups. One of the cells differentiates as R7 and the remaining as any one of the R1 to R6. The last cells behave initially as equivalent, and can differentiate within the same or within different, but neighbouring, ommatidia. The class of R1 to R6 cell in which each one of these elements differentiates, seems to depend on the time of its origin. The implications of these findings for the formation of the ommatidial pattern are discussed.
Similar content being viewed by others
References
Becker, H.J.: Über Röntgenmosaikflecken und Defektmutationen am Auge vonDrosophila und die Entwicklungsphysiologie des Auges. Z. indukt. Abstamm. u. Vererb.-L.88, 333–373 (1957)
Benzer, S.: From the gene to behavior. J. Am. Med. Assn.218, 1015–1022 (1971)
Benzer, S.: Genetic dissection of behaviour. Scient. Am.229 (12), 24–37 (1972)
Bernard, F.: Recherches sur la morphogénèse des yeux composés d'arthropodes. Bull. biol. Fr. Belg. (Suppl.)23, 1–162 (1937)
Campos-Ortega, J.A., Gateff, E.A.: The development of ommatidial patterning in metamorphosed eye imaginal disc implants ofDrosophila melanogaster. Wilhelm Roux's Archives179, 373–392 (1976)
Crick, F.H.C., Lawrence, P.A.: Compartments and polyclones in insect development. Science189, 340–347 (1975)
Fristrom, D.: Cellular degeneration in the production of some mutant phenotypes inDrosophila melanogaster. Molec. Gen. Genetics,103, 363–379 (1969)
Garcia-Bellido, A.: Pattern formation in imaginal disks. In: The biology of imaginal disks (eds., H. Ursprung and R. Nöthiger), pp. 59–91. Berlin. Heidelberg, New York: Springer-Verlag 1972
Garcia-Bellido, A., Merriam, J.R.: Parameters of the wing imaginal disc development ofDrosophila melanogaster. Dev. Biol.24, 61–87 (1971)
Garcia-Bellido, A., Ripoll, P., Morata, G.: Developmental compartmentalisation of the wing disk ofDrosophila. Nature New Biology245, 251–253 (1973)
Garcia-Bellido, A., Ripoll, P., Morata, G.: Developmental compartmentalization in the dorsal mesothoracic disk ofDrosophila. Dev. Biol.48, 132–147 (1976)
Haendle, J.: Röntgeninduzierte mitotische Rekombination beiDrosophila melanogaster: I. Ihre Abhängigkeit von der Dosis, der Dosisrate und vom Spektrum. Molec. gen. Genet.113, 114–131 (1971)
Hanson, T.E., Ready, D.F., Benzer, S.: Use of mosaics in the analysis of pattern formation in the retina ofDrosophila. An. Rep. Div. Biol. Cal. Inst. Technol. 40 (1972)
Harris, W., Stark, W., Walker, J.: Genetic dissection of the photoreceptor system in the compound eye ofDrosophila melanogaster. J. Physiol. (Lond.)256 415–439 (1976)
Hofbauer, A., Campos-Ortega, J.A.: Cell clones and pattern formation: Genetic eye mosaics inDrosophila melanogaster, Wilhelm Roux's Archives179, 275–289 (1976)
Kirschfeld, K.: Das neurale Superpositionsauge. Fortsch. Zool.21, 229–257 (1973)
Lindsley, D.L., Grell, E.H.: Genetic variations ofDrosophila melanogaster. Carnegie Inst. Wash. Publ. 627 (1968)
Melamed, J., Trujillo-Cénoz, O.: The fine structure of the central cells in the ommatidia of Dipterans. J. Ultrastr. Res.21, 313–334 (1968)
Morata, G., Ripoll, P.: Minutes: mutants ofDrosophila autonomously affecting cell division rate. Dev. Biol.42, 211–221 (1975)
Ready, D.F.: Pattern formation in the retina ofDrosophila. An. Rep. Div. Biol. Cal. Inst. Technol. 203 (1973)
Ready, D.F.: Cell proliferation and pattern formation in the developing eye ofDrosophila. An. Rep. Div. Biol. Cal. Inst. Technol. 106 (1974)
Ready, D.F.: Prepatterns in the developingDrosophila eye. An. Rep. Div. Biol. Cal. Inst. Technol. 73 (1975)
Shelton, P.M., Lawrence, P.A.: Structure and development of ommatidia inOncopeltus fasciatus. J. Embryol. exp. Morph.32, 337–353 (1974)
Stern, C., Tokunaga, C.: On cell lethals inDrosophila. Proc. Natl. Acad. Sci. USA68, 329–331 (1971)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Campos-Ortega, J.A., Hofbauer, A. Cell clones and pattern formation: On the lineage of photoreceptor cells in the compound eye ofDrosophila . Wilhelm Roux' Archiv 181, 227–245 (1977). https://doi.org/10.1007/BF00848423
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00848423