Abstract
Injection of cycloheximide into rats was shown not to change the acid and alkaline ribonuclease (RNase) activity in the cytoplasm of liver cells. Meanwhile inhibition of protein synthesis by cycloheximide led to a decrease in RNase activity of microsomes and membrane-bound polysomes. RNase activity of free polysomes in liver cells was considerably increased after administration of cycloheximide.
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Arbuzov, V.A., Krechetova, G.D. Changes in intracellular ribonuclease activity in the rat liver during inhibition of protein synthesis by cycloheximide. Bull Exp Biol Med 89, 142–144 (1980). https://doi.org/10.1007/BF00831002
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DOI: https://doi.org/10.1007/BF00831002