Summary
Six non-anaesthetized Large White pigs (mean body weight 59 ± 1.7 kg) were fitted with permanent catheters in the portal vein, the brachiocephalic artery and the right hepatic vein as well as with electromagnetic flow probes around the portal vein and around the hepatic artery. The animals were given a basal none-fibre diet (diet A) alone or together with 6% guar gum (diet B) or 15% purified cellulose (diet C). The diets were given for one week and according to a replicated 3 × 3 latin square design. On the last day of each such adaptation period test meals of 800 g were given prior to blood samplings. These samplings were continued for 8 h. Guar gum strongly reduced the amino acids (aa) and urea absorption as well as the hepatic production of urea. The aa profile of the absorbed mixture was not strongly modified by guar gum ingestion as well as the profile of the hepatic aa uptake. Cellulose at the consumed level had very few effects on the considered parameters.
It is suggested that the modulation of intestinal mechanisms by guar gum was sufficient to mediate the latter internal metabolic effects.
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Simoes Nunes, C., Malmöf, K. Interorgan movements of amino acid in the pig: effects of dietary fibres. Amino Acids 2, 77–86 (1992). https://doi.org/10.1007/BF00806077
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DOI: https://doi.org/10.1007/BF00806077