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Factors in posttranscription regulation of the rate of liver catalase synthesis in rats with tumors

  • Biochemistry and Biophysics
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The state of factors controlling the rate of catalase synthesis in the rat liver at posttranscription stages under normal conditions and during the development of a malignant tumor (2nd, 7th, and 14th days after inoculation of Pliss lymphosarcoma) was investigated. A simple method is suggested for determining the biological activity of two factors — activator (Fact) and inhibitor (Fin). The results showed that if Fact/Fin≥1, catalase synthesis is observed (2nd and 14th days after inoculation of the tumor), but if Fact/Fin<1, synthesis of the enzyme is completely suppressed (7th day after inoculation of the tumor).

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Authors
  1. V. P. Komov
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  2. T. F. Rakhmanina
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  3. A. D. Bulat
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Komov, V.P., Rakhmanina, T.F. & Bulat, A.D. Factors in posttranscription regulation of the rate of liver catalase synthesis in rats with tumors. Bull Exp Biol Med 81, 352–354 (1976). https://doi.org/10.1007/BF00804917

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  • DOI: https://doi.org/10.1007/BF00804917

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